European heart rhythm association (EHRA)/heart rhythm society (HRS)/Asia pacific heart rhythm society (APHRS)/latin American heart rhythm society (LAHRS) expert …

AAM Wilde, C Semsarian, MF Márquez, AS Shamloo… - Europace, 2022 - academic.oup.com
Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action

E Marijon, K Narayanan, K Smith, S Barra, C Basso… - The Lancet, 2023 - thelancet.com
Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD)
continues to be an enormous medical and societal challenge, claiming millions of lives …

Subepicardial cardiomyopathy: a disease underlying J-wave syndromes and idiopathic ventricular fibrillation

C Miles, BJ Boukens, C Scrocco, AAM Wilde… - Circulation, 2023 - Am Heart Assoc
Brugada syndrome (BrS), early repolarization syndrome (ERS), and idiopathic ventricular
fibrillation (iVF) have long been considered primary electrical disorders associated with …

Concealed cardiomyopathy in autopsy-inconclusive cases of sudden cardiac death and implications for families

JC Isbister, N Nowak, L Yeates, ES Singer… - Journal of the American …, 2022 - jacc.org
Background Genetic testing following sudden cardiac death (SCD) is currently guided by
autopsy findings, despite the inherent challenges of autopsy examination and mounting …

[PDF][PDF] Developed in partnership with and endorsed by the European Heart Rhythm Association (EHRA), a branch of the European Society of Cardiology (ESC), the …

MJ Ackerman, EA Ashley, EB Sternick… - Europace, 2022 - boa.unimib.it
Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

Predicted Deleterious Variants in Cardiomyopathy Genes Prognosticate Mortality and Composite Outcomes in the UK Biobank

B Asatryan, RA Shah, G Sharaf Dabbagh… - Heart Failure, 2024 - jacc.org
Background Inherited cardiomyopathies present with broad variation of phenotype. Data are
limited regarding genetic screening strategies and outcomes associated with predicted …

[PDF][PDF] From gene-discovery to gene-tailored clinical management: 25 years of research in channelopathies and cardiomyopathies

L Crotti, P Brugada, H Calkins, P Chevalier, G Conte… - Europace, 2023 - academic.oup.com
In the early nineties, few years before the birth of Europace, the clinical and scientific world
of familial arrhythmogenic conditions was revolutionized by the identification of the first …

Genetics in probands with idiopathic ventricular fibrillation: a multicenter study

L Pannone, A Gauthey, G Conte, R Osei… - Clinical …, 2023 - jacc.org
Background Different genes have been associated with idiopathic ventricular fibrillation
(IVF); however, there are no studies correlating genotype with phenotype. Objectives The …

Application of next-generation sequencing in cardiology: current and future precision medicine implications

E Papadopoulou, D Bouzarelou, G Tsaousis… - Frontiers in …, 2023 - frontiersin.org
Inherited cardiovascular diseases are highly heterogeneous conditions with multiple genetic
loci involved. The application of advanced molecular tools, such as Next Generation …

Implantable cardioverter defibrillator use in arrhythmogenic right ventricular cardiomyopathy in North America and Europe

RT Carrick, C De Marco, A Gasperetti… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims Implantable cardioverter-defibrillators (ICDs) are critical for
preventing sudden cardiac death (SCD) in arrhythmogenic right ventricular cardiomyopathy …