Sex and gender in neurodevelopmental conditions

S Bölte, J Neufeld, PB Marschik, ZJ Williams… - Nature Reviews …, 2023 - nature.com
Health-related conditions often differ qualitatively or quantitatively between individuals of
different birth-assigned sexes and gender identities, and/or with different gendered …

Autism presentation in female and Black populations: Examining the roles of identity, theory, and systemic inequalities

MC Diemer, ED Gerstein, A Regester - Autism, 2022 - journals.sagepub.com
The prevalence of autism is rising, a dynamic attributed to numerous explanations (eg better
diagnostic practices, decreased stigma). As this neurodevelopmental disability increases in …

Sex differences in autism spectrum disorder: evidence from a large sample of children and adolescents

W Mandy, R Chilvers, U Chowdhury, G Salter… - Journal of autism and …, 2012 - Springer
Sex differences have been found amongst toddlers and young children with autism
spectrum disorder (ASD). We investigated the presence and stability of these ASD sex …

The female protective effect against autism spectrum disorder

EM Wigdor, DJ Weiner, J Grove, JM Fu, WK Thompson… - Cell Genomics, 2022 - cell.com
Autism spectrum disorder (ASD) is diagnosed three to four times more frequently in males
than in females. Genetic studies of rare variants support a female protective effect (FPE) …

Sex differences on the ADOS-2

HM Rea, RA Øien, F Shic, SJ Webb… - Journal of Autism and …, 2023 - Springer
The sex difference in the prevalence of autism spectrum disorder (ASD) may be magnified
by sex differences on diagnostic measures. The current study compared autistic males and …

Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure

V Hollestein, G Poelmans, NJ Forde… - Translational …, 2023 - nature.com
The excitatory/inhibitory (E/I) imbalance hypothesis posits that imbalance between excitatory
(glutamatergic) and inhibitory (GABAergic) mechanisms underlies the behavioral …

Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders

Y Xia, C Xia, Y Jiang, Y Chen, J Zhou, R Dai… - Science Translational …, 2024 - science.org
Many psychiatric disorders exhibit sex differences, but the underlying mechanisms remain
poorly understood. We analyzed transcriptomics data from 2160 postmortem adult prefrontal …

Diagnostic tools for autism spectrum disorders by gender: Analysis of current status and future lines

E Navarro-Pardo, MF López-Ramón, Y Alonso-Esteban… - Children, 2021 - mdpi.com
Studies on the prevalence of autism spectrum disorders have shown gender disproportion.
In recent years, there has been an increasing interest in this investigation area. There are …

Dysregulation of the Wnt/β-catenin signaling pathway via Rnf146 upregulation in a VPA-induced mouse model of autism spectrum disorder

G Park, WE Jang, S Kim, EL Gonzales, J Ji… - … & Molecular Medicine, 2023 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with impaired
social behavior and communication, repetitive behaviors, and restricted interests. In addition …

A systematic review of problematic video-game use in people with Autism Spectrum Disorders

F Craig, F Tenuta, A De Giacomo, A Trabacca… - Research in Autism …, 2021 - Elsevier
Background In recent years, an increasing number of studies documented potential links
between gaming disorders (GD; including “digital-gaming” or “video-gaming”) and Autism …