In single-cell analysis, biological variability can be attributed to individual cells, their specific
state, and the ability to respond to external stimuli, which are determined by protein …

Proteomics continues to forge significant strides in the discovery of essential biological
processes, uncovering valuable information on the identity, global protein abundance …

Biopharmaceutical products have seen rapid growth over the past few decades and
continue to dominate the global pharmaceutical market. Aligning with the quality by design …

Single-cell proteomics (SCP) reveals phenotypic heterogeneity by profiling individual cells,
their biological states and functional outcomes upon signaling activation that can hardly be …

Advanced liquid chromatogram-mass spectrometry (LC-MS) and automated large-scale
data processing have made MS-based quantitative analysis increasingly useful for research …

Sequencing the tyrosine phosphoproteome using MS‐based proteomics is challenging due
to the low abundance of tyrosine phosphorylation in cells, a challenge compounded in …

Functional interactions between cytotoxic T cells and tumor cells are central to anti-cancer
immunity. However, our understanding of the proteins involved is limited. Here, we present …

Mass spectrometry (MS)-based proteomic measurements are uniquely poised to impact the
development of cell and gene therapies. With the adoption of rigorous instrumental …

Protein phosphorylation introduces post‐genomic diversity to proteins, which plays a crucial
role in various cellular activities. Elucidation of system‐wide signaling cascades requires …

Chimeric antigen receptor (CAR) T cells have transformed the landscape of cancer therapy
and demonstrate unprecedented success in treating relapsed/refractory blood cancers. The …