The first practice of pre-implantation genetic testing (PGT) was reported more than 30 years
ago. PGT, originally named preimplantation genetic screening (PGS) and pre-implantation …

Preimplantation genetic testing using polygenic risk scores (PGT-P) has recently been
introduced. However, PGT-P has been met with many ethical concerns. It is therefore …

BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …

STUDY QUESTION Would the different regulatory approaches for preimplantation genetic
testing (PGT) in Europe permit the implementation of preimplantation genetic testing using …

Background De novo mutations (DNMs) are linked with many severe early-onset disorders
ranging from rare congenital malformation to intellectual disability. Conventionally, DNMs …

The recent commercialization of the Embryo Health Score (EHS), determined through
preimplantation genetic testing for polygenic conditions, offers the potential to select …

With the increasing maturity and widespread application of assisted reproductive technology
(ART), more attention has been paid to the health outcomes of offspring following ART. It is …

Pre-implantation genetic testing (PGT) is a vital tool in preventing chromosomal
aneuploidies and other genetic disorders including those that are monogenic in origin. It is …

STUDY QUESTION Does trophectoderm biopsy (TEBx) of blastocysts for preimplantation
genetic testing in the clinic affect normal placental and embryo development and offspring …

This article examines the scope and limitations of the precision medicine paradigm and its
relationship with the collective health approach. To that end, it takes preimplantation genetic …