Arrhythmias in pregnancy
KP Tamirisa, U Elkayam, JE Briller, PK Mason… - Clinical …, 2022 - jacc.org
Increasing maternal mortality and incidence of arrhythmias in pregnancy have been noted
over the past 2 decades in the United States. Pregnancy is associated with a greater risk of …
over the past 2 decades in the United States. Pregnancy is associated with a greater risk of …
Environmental risk factors for congenital heart disease
JI Kalisch-Smith, N Ved… - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
Congenital heart disease (CHD) has many forms and a wide range of causes. Clinically, it is
important to understand the causes. This allows estimation of recurrence rate, guides …
important to understand the causes. This allows estimation of recurrence rate, guides …
[HTML][HTML] The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the
main embryonic arteries. The onset of circulation triggers several processes that provide …
main embryonic arteries. The onset of circulation triggers several processes that provide …
Modest and severe maternal iron deficiency in pregnancy are associated with fetal anaemia and organ-specific hypoxia in rats
AG Woodman, AS Care, Y Mansour, SJ Cherak… - Scientific reports, 2017 - nature.com
Prenatal iron-deficiency (ID) is known to alter fetal developmental trajectories, which
predisposes the offspring to chronic disease in later life, although the underlying …
predisposes the offspring to chronic disease in later life, although the underlying …
Early gestational hypoxia and adverse developmental outcomes
HE Ritchie, DJ Oakes, D Kennedy… - Birth Defects …, 2017 - Wiley Online Library
Hypoxia is a normal and essential part of embryonic development. However, this state may
leave the embryo vulnerable to damage when oxygen supply is disturbed. Embryofetal …
leave the embryo vulnerable to damage when oxygen supply is disturbed. Embryofetal …
Ondansetron and teratogenicity in rats: Evidence for a mechanism mediated via embryonic hERG blockade
B Danielsson, WS Webster, HE Ritchie - Reproductive Toxicology, 2018 - Elsevier
The potent hERG channel blocking drug ondansetron is used off-label for treatment of
nausea and vomiting in early pregnancy. Some human epidemiological studies have …
nausea and vomiting in early pregnancy. Some human epidemiological studies have …
Effects of pre-and postnatal exposure to 1880–1900 MHz DECT base radiation on development in the rat
M Stasinopoulou, AF Fragopoulou, A Stamatakis… - Reproductive …, 2016 - Elsevier
In the present study, to evaluate the effects of wireless 1880–1900 MHz Digital Enhanced
Communication Telephony (DECT) base radiation on fetal and postnatal development …
Communication Telephony (DECT) base radiation on fetal and postnatal development …
[HTML][HTML] Antiarrhythmic Drug Use in Pregnancy: Considerations and Safety Profiles
MV Mariani, N Pierucci, VM La Fazia… - Journal of …, 2024 - mdpi.com
Pregnancy entails notable physiological alterations and hormonal fluctuations that affect the
well-being of both the fetus and the mother. Cardiovascular events and arrhythmias are a …
well-being of both the fetus and the mother. Cardiovascular events and arrhythmias are a …
The effects of nifedipine and ivabradine on the functionality of the early rat embryonic heart. Are these drugs a risk in early human pregnancy?
HE Ritchie, C Telenius, E Gustaffson… - Birth Defects …, 2019 - Wiley Online Library
Background When the human heart begins its earliest contractions from day 21, it lacks a
functional autonomic nerve supply. Instead, contractions are generated by regular calcium …
functional autonomic nerve supply. Instead, contractions are generated by regular calcium …
The effect of phenytoin on embryonic heart rate in Vivo
Phenytoin is a known human teratogen with unknown etiology. Several mechanisms have
been proposed including disturbances in folate metabolism, induction of embryonic hypoxia …
been proposed including disturbances in folate metabolism, induction of embryonic hypoxia …