Applications of guanine quartets in nanotechnology and chemical biology

L Stefan, D Monchaud - Nature Reviews Chemistry, 2019 - nature.com
Guanine and related nucleobases such as guanosine, deoxyguanosine and isoguanosine
are notable molecular tools for designing functional supramolecular assemblies. This …

Thermodynamic stability of G‐quadruplexes: impact of sequence and environment

J Jana, K Weisz - ChemBioChem, 2021 - Wiley Online Library
G‐quadruplexes have attracted growing interest in recent years due to their occurrence in
vivo and their possible biological functions. In addition to being promising targets for drug …

Understanding chemical reactivity using the activation strain model

P Vermeeren, SCC van der Lubbe… - Nature protocols, 2020 - nature.com
Understanding chemical reactivity through the use of state-of-the-art computational
techniques enables chemists to both predict reactivity and rationally design novel reactions …

How the Chalcogen Atom Size Dictates the Hydrogen‐Bond Donor Capability of Carboxamides, Thioamides, and Selenoamides

C Nieuwland, C Fonseca Guerra - Chemistry–A European …, 2022 - Wiley Online Library
The amino groups of thio‐and selenoamides can act as stronger hydrogen‐bond donors
than of carboxamides, despite the lower electronegativity of S and Se. This phenomenon …

New insights on the interaction of phenanthroline based ligands and metal complexes and polyoxometalates with duplex DNA and G-quadruplexes

Á Sánchez-González, NAG Bandeira… - Molecules, 2021 - mdpi.com
This work provides new insights from our team regarding advances in targeting canonical
and non-canonical nucleic acid structures. This modality of medical treatment is used as a …

Learning to model G-quadruplexes: current methods and perspectives

I Ortiz de Luzuriaga, X Lopez… - Annual Review of …, 2021 - annualreviews.org
G-quadruplexes have raised considerable interest during the past years for the development
of therapies against cancer. These noncanonical structures of DNA may be found in …

Potassium as the best alkali metal promoter in boosting the hydrogenation activity of Ru/MgO for aromatic LOHC molecules by facilitated heterolytic H2 adsorption

TW Kim, D Kim, Y Jo, HJ Jung, JH Park, YW Suh - Journal of Catalysis, 2023 - Elsevier
Alkali metals (AM) are frequently used as promoters in a number of reactions. In aromatic
hydrogenation over Ru/MgO, their basicity may promote heterolytic H 2 adsorption, thereby …

Structure and dynamics of RNA guanine quadruplexes in SARS-CoV-2 genome. Original strategies against emerging viruses

T Miclot, C Hognon, E Bignon, A Terenzi… - The Journal of …, 2021 - ACS Publications
Guanine quadruplex (G4) structures in the viral genome have a key role in modulating
viruses' biological activity. While several DNA G4 structures have been experimentally …

RNA versus DNA G‐Quadruplex: The Origin of Increased Stability

F Zaccaria, C Fonseca Guerra - Chemistry–A European …, 2018 - Wiley Online Library
DNA quadruplexes have been the subject of investigation because of their biological
relevance and because of their potential application in supramolecular chemistry. Similarly …

G-quadruplexes from non-coding RNAs

F Li, J Zhou - Journal of Molecular Medicine, 2023 - Springer
Non-coding RNAs (ncRNAs) are significant regulators of gene expression in a wide range of
biological processes, such as transcription, RNA maturation, or translation. ncRNAs …