[HTML][HTML] Pros and cons of different therapeutic antibody formats for recombinant antivenom development
Antibody technologies are being increasingly applied in the field of toxinology. Fuelled by
the many advances in immunology, synthetic biology, and antibody research, different …
the many advances in immunology, synthetic biology, and antibody research, different …
Ending the drought: new strategies for improving the flow of affordable, effective antivenoms in Asia and Africa
The development of snake antivenoms more than a century ago should have heralded
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …
Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming.
The efficacy of antivenoms to neutralize toxicity of medically-relevant snake venoms has to …
The efficacy of antivenoms to neutralize toxicity of medically-relevant snake venoms has to …
Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability …
We describe two geographically differentiated venom phenotypes across the wide
distribution range of Bothrops atrox, from the Colombian Magdalena Medio Valley through …
distribution range of Bothrops atrox, from the Colombian Magdalena Medio Valley through …
Bleeding and Thrombosis: Insights into Pathophysiology of Bothrops Venom-Related Hemostasis Disorders
S Larréché, JP Chippaux, L Chevillard… - International Journal of …, 2021 - mdpi.com
Toxins from Bothrops venoms targeting hemostasis are responsible for a broad range of
clinical and biological syndromes including local and systemic bleeding, incoagulability …
clinical and biological syndromes including local and systemic bleeding, incoagulability …
Comparison of phylogeny, venom composition and neutralization by antivenom in diverse species of Bothrops complex
LF Sousa, CA Nicolau, PS Peixoto… - PLoS neglected …, 2013 - journals.plos.org
In Latin America, Bothrops snakes account for most snake bites in humans, and the
recommended treatment is administration of multispecific Bothrops antivenom (SAB–soro …
recommended treatment is administration of multispecific Bothrops antivenom (SAB–soro …
Antivenoms for the treatment of snakebite envenomings: the road ahead
The parenteral administration of antivenoms is the cornerstone of snakebite envenoming
therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are …
therapy. Efforts are made to ensure that antivenoms of adequate efficacy and safety are …
New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India
The direct estimate of 46,000 snakebite deaths in India in 2005 (1 for every 2 HIV/AIDS
deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite …
deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite …
Priority actions and progress to substantially and sustainably reduce the mortality, morbidity and socioeconomic burden of tropical snakebite
RA Harrison, JM Gutiérrez - 2016 - mdpi.com
The deliberations and conclusions of a Hinxton Retreat convened in September 2015,
entitled “Mechanisms to reverse the public health neglect of snakebite victims” are reported …
entitled “Mechanisms to reverse the public health neglect of snakebite victims” are reported …
[HTML][HTML] Envenenamientos por mordeduras de serpientes en América Latina y el Caribe: Una visión integral de carácter regional
JM Gutiérrez - Boletín de malariología y salud ambiental, 2011 - ve.scielo.org
Se analiza la situación de los envenenamientos por mordeduras de serpiente en América
Latina y el Caribe, los cuales representan un importante problema de Salud Pública en la …
Latina y el Caribe, los cuales representan un importante problema de Salud Pública en la …