Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications
Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering,
regenerative medicine, and drug delivery applications due to their specific characteristics …
regenerative medicine, and drug delivery applications due to their specific characteristics …
Stem cell differentiation is regulated by extracellular matrix mechanics
Stem cells mechanosense the stiffness of their microenvironment, which impacts
differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix …
differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix …
[HTML][HTML] Designing degradable hydrogels for orthogonal control of cell microenvironments
Degradable and cell-compatible hydrogels can be designed to mimic the physical and
biochemical characteristics of native extracellular matrices and provide tunability of …
biochemical characteristics of native extracellular matrices and provide tunability of …
[HTML][HTML] A guide to mechanobiology: Where biology and physics meet
KA Jansen, DM Donato, HE Balcioglu, T Schmidt… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Cells actively sense and process mechanical information that is provided by the extracellular
environment to make decisions about growth, motility and differentiation. It is important to …
environment to make decisions about growth, motility and differentiation. It is important to …
25th anniversary article: designer hydrogels for cell cultures: a materials selection guide
Cell culturing, whether for tissue engineering or cell biology studies, always involves placing
cells in a non‐natural environment and no material currently exist that can mimic the entire …
cells in a non‐natural environment and no material currently exist that can mimic the entire …
Physical cues of biomaterials guide stem cell differentiation fate
Millions of people lose or damage their organs or tissues due to disease, birth defects, or
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …
accidents each year. Stem cells, such as embryonic stem cells (ESCs), induced pluripotent …
Electrical and mechanical stimulation of cardiac cells and tissue constructs
The field of cardiac tissue engineering has made significant strides over the last few
decades, highlighted by the development of human cell derived constructs that have shown …
decades, highlighted by the development of human cell derived constructs that have shown …
[HTML][HTML] Stem cell mechanobiology and the role of biomaterials in governing mechanotransduction and matrix production for tissue regeneration
SM Naqvi, LM McNamara - Frontiers in bioengineering and …, 2020 - frontiersin.org
Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …
Physics of adherent cells
US Schwarz, SA Safran - Reviews of Modern Physics, 2013 - APS
One of the most unique physical features of cell adhesion to external surfaces is the active
generation of mechanical force at the cell-material interface. This includes pulling forces …
generation of mechanical force at the cell-material interface. This includes pulling forces …
[HTML][HTML] Mechanotransduction: use the force (s)
Mechanotransduction-how cells sense physical forces and translate them into biochemical
and biological responses-is a vibrant and rapidly-progressing field, and is important for a …
and biological responses-is a vibrant and rapidly-progressing field, and is important for a …