Cellular, molecular, and clinical mechanisms of action of deep brain stimulation—a systematic review on established indications and outlook on future developments

M Jakobs, A Fomenko, AM Lozano… - EMBO molecular …, 2019 - embopress.org
Deep brain stimulation (DBS) has been successfully used to treat movement disorders, such
as Parkinson's disease, for more than 25 years and heralded the advent of electrical …

Deep brain stimulation treating dystonia: a systematic review of targets, body distributions and etiology classifications

H Fan, Z Zheng, Z Yin, J Zhang, G Lu - Frontiers in Human …, 2021 - frontiersin.org
Background: Deep brain stimulation (DBS) is a typical intervention treating drug-refractory
dystonia. Currently, the selection of the better target, the GPi or STN, is debatable. The …

Pharmacological and neurosurgical interventions for individuals with cerebral palsy and dystonia: a systematic review update and meta‐analysis

E Bohn, K Goren, L Switzer… - … Medicine & Child …, 2021 - Wiley Online Library
Aim To update a systematic review of evidence published up to December 2015 for
pharmacological/neurosurgical interventions among individuals with cerebral palsy (CP) …

GNAO1-related movement disorder: an update on phenomenology, clinical course, and response to treatments

M Novelli, S Galosi, G Zorzi, S Martinelli… - Parkinsonism & Related …, 2023 - Elsevier
Aim To evaluate clinical phenotype and molecular findings of 157 cases with GNAO1
pathogenic or likely pathogenic variants delineating the clinical spectrum, course, and …

Deep brain stimulation for refractory status dystonicus in children: multicenter case series and systematic review

LM Vogt, H Yan, B Santyr, S Breitbart… - Annals of …, 2024 - Wiley Online Library
Objective We sought to better understand the workflow, outcomes, and complications of
deep brain stimulation (DBS) for pediatric status dystonicus (SD). We present a systematic …

Juvenile parkinsonism: Differential diagnosis, genetics, and treatment

N Niemann, J Jankovic - Parkinsonism & related disorders, 2019 - Elsevier
Juvenile parkinsonism is arbitrarily defined as parkinsonian symptoms and signs presenting
prior to 21 years of age. Levodopa-responsive juvenile parkinsonism that is consistent with …

Towards functional improvement of motor disorders associated with cerebral palsy

S Bekteshi, E Monbaliu, S McIntyre, G Saloojee… - The Lancet …, 2023 - thelancet.com
Cerebral palsy is a lifelong neurodevelopmental condition arising from non-progressive
disorders occurring in the fetal or infant brain. Cerebral palsy has long been categorised into …

Effect of levothyroxine therapy on the development of depressive symptoms in older adults with subclinical hypothyroidism: an ancillary study of a randomized clinical …

L Wildisen, M Feller, C Del Giovane… - JAMA network …, 2021 - jamanetwork.com
Importance Previous trials on the effect of levothyroxine on depressive symptom scores in
patients with subclinical hypothyroidism were limited by small sample sizes (N= 57 to 94) …

Deep brain stimulation for Gilles de la Tourette syndrome in children and youth: a meta-analysis with individual participant data

MA Coulombe, LM Elkaim, NM Alotaibi… - Journal of …, 2018 - thejns.org
OBJECTIVE Gilles de la Tourette syndrome (GTS) is a disorder characterized by motor and
vocal tics. Although by definition the onset of GTS is before age 18 years, clinical trials of …

Status dystonicus in children: a cross-sectional study and review of literature

AG Saini, I Hassan, K Sharma… - Journal of Child …, 2022 - journals.sagepub.com
Background: Status dystonicus is a life-threatening, underrecognized movement disorder
emergency. We aimed to ascertain the etiology, clinical presentation, complications, and …