The generation of appropriate behavioral responses involves dedicated neuronal circuits.
The cortico-striatal-thalamo-cortical loop is especially important for the expression of motor …

Prolonged exposure (PE) therapy aiming to promote fear extinction is a useful treatment for
post-traumatic stress disorder (PTSD). However, the mechanisms underlying fear extinction …

Depression is one of the most common psychiatric diseases worldwide. With the increase in
the number of depressive episodes, cognitive dysfunction may be accelerated. Although …

For decades, researchers have studied how brain tumors, the immune system, and drugs
interact. With the advances in cancer neuroscience, which centers on defining and …

Cognitive dysfunction caused by diabetes has become a serious global medical issue.
Diabetic kidney disease (DKD) exacerbates cognitive dysfunction in patients, although the …

Disturbances in cholesterol homeostasis have been associated with ASD. Lipid rafts are
central in many transmembrane signaling pathways (including mTOR) and changes in raft …

Mutations of TRAPPC12 are associated with progressive childhood encephalopathy
including abnormal white matter. However, the underlying pathogenesis is still unclear …

Diesel exhaust particles (DEPs) are major air pollutants emitted from automobile engines.
Prenatal exposure to DEPs has been linked to neurodevelopmental and neurodegenerative …

PM2. 5 exposure is a challenging environmental issue that is closely related to cognitive
development impairment; however, currently, relevant means for prevention and treatment …

Vascular dementia (VaD) has a serious impact on the patients' quality of life. Icariin (Ica)
possesses neuroprotective potential for treating VaD, yet its oral bioavailability and blood …