Dystrophin is a 427 kDa sub-membrane cytoskeletal protein, associated with the inner
surface membrane and incorporated in a large macromolecular complex of proteins, the …

It is commonly recognized in the field that cancer cells exhibit changes in the size and shape
of their nuclei. These features often serve as important biomarkers in the diagnosis and …

Dystroglycan is a cell membrane protein that binds to the extracellular matrix in a variety of
mammalian tissues. The α-subunit of dystroglycan (αDG) is heavily glycosylated, including a …

ROS-activated cSrc tyrosine kinase (TK) promotes the degradation of β-dystroglycan (β-DG),
a dystrophin-glycoprotein complex component, which may reinforce damaging signals in …

Dystroglycan (DG) is a glycoprotein composed of two subunits that remain non-covalently
bound at the plasma membrane: α-DG, which is extracellular and heavily O-mannosyl …

Dystroglycan is frequently lost in adenocarcinoma, but the mechanisms and consequences
are poorly understood. We report an analysis of β-dystroglycan in prostate cancer in human …

Identification of a systemically acting and universal small molecule therapy for Duchenne
muscular dystrophy would be an enormous advance for this condition. Based on evidence …

Dystroglycan is a ubiquitously expressed heterodimeric cell-surface laminin receptor with
roles in cell adhesion, signalling, and membrane stabilisation. More recently, the …

Even though the Duchenne muscular dystrophy (DMD) gene product Dystrophin Dp71d is
involved in various key cellular processes through its role as a scaffold for structural and …

The function of muscle is to contract, which means to exert force on a substrate. The
adaptations required for skeletal muscle differentiation, from a prototypic cell, involve …