High-resolution computed tomography for clinical imaging of bone microarchitecture

AJ Burghardt, TM Link, S Majumdar - Clinical Orthopaedics and …, 2011 - journals.lww.com
Background The role of bone structure, one component of bone quality, has emerged as a
contributor to bone strength. The application of high-resolution imaging in evaluating bone …

Microcomputed tomography: approaches and applications in bioengineering

JD Boerckel, DE Mason, AM McDermott… - Stem cell research & …, 2014 - Springer
Microcomputed tomography (microCT) has become a standard and essential tool for
quantifying structure-function relationships, disease progression, and regeneration in …

Trends in synchrotron-based tomographic imaging: the SLS experience

M Stampanoni, A Groso, A Isenegger… - Developments in X …, 2006 - spiedigitallibrary.org
Synchrotron-based X-ray Tomographic Microscopy (SRXTM) is nowadays a powerful
technique for non-destructive, high-resolution investigations of a broad kind of materials …

Age-related transparent root dentin: mineral concentration, crystallite size, and mechanical properties

JH Kinney, RK Nalla, JA Pople, TM Breunig, RO Ritchie - Biomaterials, 2005 - Elsevier
Many fractures occur in teeth that have been altered, for example restored or endodontically
repaired. It is therefore essential to evaluate the structure and mechanical properties of …

Characterization and some physicochemical aspects of pathological microcalcifications

D Bazin, M Daudon, C Combes, C Rey - Chemical Reviews, 2012 - ACS Publications
Several major diseases, such as cancer and cardiovascular abnormalities, may be linked to
pathological deposition of minerals or organic compounds in various tissues. 1− 3 Thus, the …

The role of mineralization and organic matrix in the microhardness of bone tissue from controls and osteoporotic patients

G Boivin, Y Bala, A Doublier, D Farlay, LG Ste-Marie… - Bone, 2008 - Elsevier
Degree of mineralization of bone (DMB) is a major intrinsic determinant of bone strength at
the tissue level but its contribution to the microhardness (Vickers indentation) at the …

Beam hardening artifacts in micro-computed tomography scanning can be reduced by X-ray beam filtration and the resulting images can be used to accurately …

JA Meganck, KM Kozloff, MM Thornton, SM Broski… - Bone, 2009 - Elsevier
Bone mineral density (BMD) measurements are critical in many research studies
investigating skeletal integrity. For pre-clinical research, micro-computed tomography (μCT) …

Bone architecture: collagen structure and calcium/phosphorus maps

M Tzaphlidou - Journal of biological physics, 2008 - Springer
Bone collagen structure in normal and pathological tissues is presented using techniques of
thin section transmission electron microscopy and morphometry. In pathological tissue …

Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone

JM Cole, JC Wood, NC Lopes, K Poder, RL Abel… - Scientific reports, 2015 - nature.com
A bright μm-sized source of hard synchrotron x-rays (critical energy E crit> 30 keV) based on
the betatron oscillations of laser wakefield accelerated electrons has been developed. The …

X-ray tomography of whole cells

MA Le Gros, G McDermott, CA Larabell - Current opinion in structural …, 2005 - Elsevier
X-ray tomography has been shown to provide insights into the internal structure of whole
cells that can't be obtained by any other means. With recent advances in instrumentation …