Non-histone protein methylation: biological significance and bioengineering potential
Protein methylation is a key post-translational modification whose effects on gene
expression have been intensively studied over the last two decades. Recently, renewed …
expression have been intensively studied over the last two decades. Recently, renewed …
Post-translational modification prediction via prompt-based fine-tuning of a GPT-2 model
Post-translational modifications (PTMs) are pivotal in modulating protein functions and
influencing cellular processes like signaling, localization, and degradation. The complexity …
influencing cellular processes like signaling, localization, and degradation. The complexity …
LMPhosSite: a deep learning-based approach for general protein phosphorylation site prediction using embeddings from the local window sequence and pretrained …
Phosphorylation is one of the most important post-translational modifications and plays a
pivotal role in various cellular processes. Although there exist several computational tools to …
pivotal role in various cellular processes. Although there exist several computational tools to …
iPromoter-Seqvec: identifying promoters using bidirectional long short-term memory and sequence-embedded features
TH Nguyen-Vo, QH Trinh, L Nguyen… - BMC genomics, 2022 - Springer
Background Promoters, non-coding DNA sequences located at upstream regions of the
transcription start site of genes/gene clusters, are essential regulatory elements for the …
transcription start site of genes/gene clusters, are essential regulatory elements for the …
Multifactorial feature extraction and site prognosis model for protein methylation data
Integrated studies (multi-omics studies) comprising genetic, proteomic and epigenetic data
analyses have become an emerging topic in biomedical research. Protein methylation is a …
analyses have become an emerging topic in biomedical research. Protein methylation is a …
Deep Learning–Based Advances In Protein Posttranslational Modification Site and Protein Cleavage Prediction
Posttranslational modification (PTM) is a ubiquitous phenomenon in both eukaryotes and
prokaryotes which gives rise to enormous proteomic diversity. PTM mostly comes in two …
prokaryotes which gives rise to enormous proteomic diversity. PTM mostly comes in two …
Accurately predicting glutarylation sites using sequential bi-peptide-based evolutionary features
Post Translational Modification (PTM) is defined as the alteration of protein sequence upon
interaction with different macromolecules after the translation process. Glutarylation is …
interaction with different macromolecules after the translation process. Glutarylation is …
A deep learning based approach for prediction of Chlamydomonas reinhardtii phosphorylation sites
Protein phosphorylation, which is one of the most important post-translational modifications
(PTMs), is involved in regulating myriad cellular processes. Herein, we present a novel deep …
(PTMs), is involved in regulating myriad cellular processes. Herein, we present a novel deep …
Recsno: prediction of protein s-nitrosylation sites using a recurrent neural network
S-Nitrosylation modification is one of the most important post-translational modifications; it
plays a critical role in a vast variety of biological processes and is related to various …
plays a critical role in a vast variety of biological processes and is related to various …
DTL-DephosSite: Deep transfer learning based approach to predict dephosphorylation sites
Phosphorylation, which is mediated by protein kinases and opposed by protein
phosphatases, is an important post-translational modification that regulates many cellular …
phosphatases, is an important post-translational modification that regulates many cellular …