Most loci identified by GWASs have been found in populations of European ancestry (EUR).
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …

Most genome-wide association and fine-mapping studies to date have been conducted in
individuals of European descent, and genetic studies of populations of Hispanic/Latino and …

Novel prognostic inflammatory markers of cancer survival and cardiovascular disease are;
the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR) and the …

Platelets are the second most abundant cell type in blood and are essential for maintaining
haemostasis. Their count and volume are tightly controlled within narrow physiological …

Genome-wide association studies (GWASs) have identified many SNPs underlying
variations in plasma-lipid levels. We explore whether additional loci associated with plasma …

To identify genetic factors contributing to type 2 diabetes (T2D), we performed large-scale
meta-analyses by using a custom∼ 50,000 SNP genotyping array (the ITMAT-Broad-CARe …

Integrating results from genome-wide association studies (GWASs) and gene expression
studies through transcriptome-wide association study (TWAS) has the potential to shed light …

Blood pressure (BP) is a heritable risk factor for cardiovascular disease. To investigate
genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure …

Variation in MPV between normal individuals is responsible for roughly a two-fold range in
platelet protein content, including key surface receptors and reactive granule constituents …

Total white blood cell (WBC) and neutrophil counts are lower among individuals of African
descent due to the common African-derived “null” variant of the Duffy Antigen Receptor for …