A hyperinflammatory response to severe acute respiratory syndrome‐coronavirus 2 (SARS‐
CoV‐2) infection, reminiscent of cytokine release syndrome, has been implicated in the …

Sepsis is a complex condition characterized by the simultaneous activation of inflammation
and coagulation in response to microbial insult. These events manifest as systemic …

Sepsis represents the host's systemic inflammatory response to a severe infection. It causes
substantial human morbidity resulting in hundreds of thousands of deaths each year …

Objective: To provide an update to the original Surviving Sepsis Campaign clinical
management guidelines,“Surviving Sepsis Campaign Guidelines for Management of Severe …

Sepsis is the leading cause of death in critically ill patients in the United States. Yet the
individual host response to septicemia is variable, depending on the patient's immune …

Objective In 2003, critical care and infectious disease experts representing 11 international
organizations developed management guidelines for severe sepsis and septic shock that …

Background Specific treatments for influenza are limited to neuraminidase inhibitors and
adamantanes. Corticosteroids show evidence of benefit in sepsis and related conditions …

ContextSeptic shock may be associated with relative adrenal insufficiency. Thus, a
replacement therapy of low doses of corticosteroids has been proposed to treat septic shock …

Background Hydrocortisone is widely used in patients with septic shock even though a
survival benefit has been reported only in patients who remained hypotensive after fluid and …

Purpose To assess the effect of low dose corticosteroids on outcomes in adults with septic
shock. Methods We systematically reviewed randomised clinical trials (RCTs) comparing …