The rapid scale-up of research on coronavirus disease 2019 (COVID-19) has spawned a
large number of potential vaccines and immunotherapies, accompanied by a …

This Perspective proposes definitions for key terms in the field of HIV-1 latency and
eradication. In the context of eradication, a reservoir is a cell type that allows persistence of …

Infection with Zika virus has been associated with serious neurological complications and
fetal abnormalities. However, the dynamics of viral infection, replication and shedding are …

The development of immunologic interventions that can target the viral reservoir in HIV-1-
infected individuals is a major goal of HIV-1 research,. However, little evidence exists that …

Neutralizing antibodies (Nab) are a principal component of an effective human immune
response to many pathogens, yet their role in HIV-1 infection is unclear,,,,,. To gain a better …

Modern viral kinetic modeling and its application to therapeutics is a field that attracted the
attention of the medical, pharmaceutical, and modeling communities during the early days of …

During the past 6 years, there have been substantial advances in our understanding of
human immunodeficiency virus 1 and other viruses, such as hepatitis B virus and hepatitis C …

The HIV-1 pandemic is a complex mix of diverse epidemics within and between countries
and regions of the world, and is undoubtedly the defining public-health crisis of our time …

Identification of full-length transmitted HIV-1 genomes could be instrumental in HIV-1
pathogenesis, microbicide, and vaccine research by enabling the direct analysis of those …

Currently, little is known about the viral kinetics of influenza A during infection within an
individual. We utilize a series of mathematical models of increasing complexity, which …