Immunohistochemistry plays an indispensable role in accurate diagnosis of malignant
mesothelioma, particularly in morphologically challenging cases and in biopsy and cytology …

Breast cancer is the most prevalent malignant tumor and main oncologic cause of mortality
in women. Although most diagnosis of breast pathology is accomplished using hematoxylin …

Since the 2015 WHO classification was introduced into clinical practice,
immunohistochemistry (IHC) has figured prominently in lung cancer diagnosis. In addition to …

Background Lung cancer, one of the most common malignant tumors, exhibits high inter-and
intra-tumor heterogeneity which contributes significantly to treatment resistance and failure …

Abstract Background Tumor protein 63 (p63) is a transcription factor of the p53 gene family
involved in differentiation of several tissues including squamous epithelium. p63 …

Pulmonary mucoepidermoid carcinoma is an uncommon but distinctive manifestation of
mucoepidermoid carcinoma. Pulmonary mucoepidermoid carcinoma occurs in adults and …

The metastasis of tumors to the stomach is rare, which underlies the clinical problems
regarding their diagnosis and treatment. The present review summarizes the current …

Ovarian clear cell adenocarcinoma has a relatively poor prognosis among the ovarian
cancer subtypes because of its high chemoresistance. Differential diagnosis of clear cell …

In lung cancer, targeted therapies depend on accurate histological subclassification of the
tumor. The majority of lung cancers can be subclassified based on hematoxylin and eosin …

Currently, non–small cell lung carcinomas are primarily classified by light microscopy.
However, recent studies have shown that poorly differentiated tumors are more accurately …