Bladder cancer, inflammageing and microbiomes

A Martin, BL Woolbright, S Umar, MA Ingersoll… - Nature Reviews …, 2022 - nature.com
Ageing is correlated with elevated bladder cancer incidence, morbidity and mortality.
Advanced age is also associated with elevated markers of chronic inflammation and …

Immunology of bile acids regulated receptors

S Fiorucci, S Marchianò, G Urbani, C Di Giorgio… - Progress in Lipid …, 2024 - Elsevier
Bile acids are steroids generated at the interface of host and intestinal microbiota. While
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …

Modulation of the PI3K/Akt/mTOR signaling pathway by probiotics as a fruitful target for orchestrating the immune response

AH Mohseni, V Casolaro, LG Bermúdez-Humarán… - Gut …, 2021 - Taylor & Francis
The mammalian target of rapamycin (mTOR) and the phosphatidylinositol-3-kinase
(PI3K)/protein kinase B or Akt (PKB/Akt) signaling pathways are considered as two but …

Engineered probiotics Clostridium butyricum‐pMTL007‐GLP‐1 improves blood pressure via producing GLP‐1 and modulating gut microbiota in spontaneous …

X Wang, W Chen, R Jin, X Xu, J Wei… - Microbial …, 2023 - Wiley Online Library
Hypertension is a significant risk factor of cardiovascular diseases (CVDs) with high
prevalence worldwide, the current treatment has multiple adverse effects and requires …

Regulation of gut microbiota-bile acids axis by probiotics in inflammatory bowel disease

L Li, T Liu, Y Gu, X Wang, R Xie, Y Sun… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is characterized by chronic and relapsing inflammation of
gastrointestinal tract, with steadily increased incidence and prevalence worldwide. Although …

Lactobacillus casei Zhang exerts anti-obesity effect to obese glut1 and gut-specific-glut1 knockout mice via gut microbiota modulation mediated different …

Q He, Y Zhang, D Ma, W Zhang, H Zhang - European journal of nutrition, 2022 - Springer
Purpose Obesity is a major risk factor for various metabolic diseases, including metabolic
syndrome and type-2 diabetes. Glucose transporter 1 (GLUT1) impairment has been …

Lactobacillus casei LH23 modulates the immune response and ameliorates DSS-induced colitis via suppressing JNK/p-38 signal pathways and enhancing histone …

M Liu, J Ding, H Zhang, J Shen, Y Hao, X Zhang… - Food & function, 2020 - pubs.rsc.org
Probiotics are thought to have immunomodulatory functions, improve inflammatory disorders
and treat inflammatory bowel disease (IBD). Here, we screened a new probiotic strain with …

[HTML][HTML] Lactobacillus fermentum CKCC1858 and Lactobacillus plantarum CKCC1312 ameliorate the symptoms of ulcerative colitis in mouse model induced by …

A Li, L Zhang, L Chen, J Wang, A Liu, P Luo… - Journal of Functional …, 2024 - Elsevier
The objective of this study was to investigate the therapeutical action of Lactobacillus
fermentum CKCC1858 and Lactobacillus plantarum CKCC1312 on ulcerative colitis (UC) …

Pediococcus acidilactici Promotes the Longevity of C. elegans by Regulating the Insulin/IGF-1 and JNK/MAPK Signaling, Fat Accumulation and Chloride Ion

R Hu, Y Zhang, W Qian, Y Leng, Y Long, X Liu… - Frontiers in …, 2022 - frontiersin.org
Probiotics are known to contribute to the anti-oxidation, immunoregulation, and aging delay.
Here, we investigated the extension of lifespan by fermented pickles-origin Pediococcus …

The preventive effects of Lactobacillus casei 03 on Escherichia coli-induced mastitis in vitro and in vivo

K Li, M Yang, M Tian, L Jia, Y Wu, J Du, L Yuan… - Journal of …, 2024 - Springer
Background Lactobacillus casei possesses many kinds of bioactivities, such as anti-
inflammation and anti-oxidant, and has been applied to treating multiple inflammatory …