Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections

P Zimmermann, N Curtis - Archives of disease in childhood, 2021 - adc.bmj.com
In contrast to other respiratory viruses, children have less severe symptoms when infected
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …

[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions

AI Abulsoud, HM El-Husseiny, AA El-Husseiny… - Biomedicine & …, 2023 - Elsevier
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

W Ni, X Yang, D Yang, J Bao, R Li, Y Xiao, C Hou… - Critical Care, 2020 - Springer
An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global …

Biomarkers associated with COVID-19 disease progression

G Ponti, M Maccaferri, C Ruini, A Tomasi… - Critical reviews in …, 2020 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a scientific, medical, and
social challenge. The complexity of the severe acute respiratory syndrome coronavirus 2 …

Human recombinant soluble ACE2 in severe COVID-19

A Zoufaly, M Poglitsch, JH Aberle… - The Lancet …, 2020 - thelancet.com
Human recombinant soluble ACE2 in severe COVID-19 - The Lancet Respiratory Medicine Skip
to Main Content Advertisement The Lancet Respiratory Medicine Submit Article Log in Register …

Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury

Y Liu, Y Yang, C Zhang, F Huang, F Wang… - Science China Life …, 2020 - Springer
The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan, Hubei
province, and rapidly spread to many provinces in China as well as other countries. Here we …

Hypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence

C Sardu, J Gambardella, MB Morelli, X Wang… - Journal of clinical …, 2020 - mdpi.com
The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …

COVID-19 in children, pregnancy and neonates: a review of epidemiologic and clinical features

P Zimmermann, N Curtis - The Pediatric infectious disease journal, 2020 - journals.lww.com
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
spread rapidly across the globe. In contrast to initial reports, recent studies suggest that …

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

EG Favalli, F Ingegnoli, O De Lucia, G Cincinelli… - Autoimmunity …, 2020 - Elsevier
The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has
quickly become a global health emergency. Given the lack of specific anti-viral therapies, the …

Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study

FJ de Abajo, S Rodríguez-Martín, V Lerma… - The Lancet, 2020 - thelancet.com
Background Concerns have been raised about the possibility that inhibitors of the renin–
angiotensin–aldosterone system (RAAS) could predispose individuals to severe COVID-19; …