Allergic diseases are on the rise in the Western world and well-known allergy-protecting and-
driving factors such as microbial and dietary exposure, pollution and smoking mediate their …

Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

DNA methylation microarrays can be employed to interrogate cell-type composition in
complex tissues. Here, we expand reference-based deconvolution of blood DNA …

Epigenome-wide association studies of disease widely use DNA methylation measured in
blood as a surrogate tissue. Cell proportions can vary between people and confound …

Background DNA methylation is an important epigenetic mark that can potentially link early
life exposures to adverse health outcomes later in life. Host factors like sex and age strongly …

Epigenetics refers to mitotically heritable changes to the DNA, which do not affect the DNA
sequence, but can influence its function. Currently, DNA methylation is the most studied …

Adiposity and obesity result from the interaction of genetic variation and environmental
factors from very early in life, possibly mediated by epigenetic processes. Few Epigenome …

In the analysis of high-throughput data from complex samples, cell composition is an
important factor that needs to be accounted for. Except for a limited number of tissues with …

The interplay of genetically driven biological processes and environmental factors is a key
driver of research questions spanning multiple areas of psychology. A nascent area of …

Background Both higher and lower fetal growth are associated with cardio-metabolic health
later in life, suggesting that prenatal developmental programming determines long-term …