Wnt signaling in brain tumors: A challenging therapeutic target

L Manfreda, E Rampazzo, L Persano - Biology, 2023 - mdpi.com
Simple Summary Wnt signaling is one of the main evolutionarily conserved developmental
pathways needed to instruct embryo formation and maintenance of organ tissues. Decades …

Molecular genetics of intracranial meningiomas with emphasis on canonical Wnt signalling

N Pećina-Šlaus, A Kafka, M Lechpammer - Cancers, 2016 - mdpi.com
Research over the last decade recognized the importance of novel molecular pathways in
pathogenesis of intracranial meningiomas. In this review, we focus on human brain tumours …

Identification of key genes with differential correlations in lung adenocarcinoma

Y Zhou, B Xu, Y Zhou, J Liu, X Zheng, Y Liu… - Frontiers in cell and …, 2021 - frontiersin.org
Background With the advent of large-scale molecular profiling, an increasing number of
oncogenic drivers contributing to precise medicine and reshaping classification of lung …

Identification of GSN and LAMC2 as key prognostic genes of bladder cancer by integrated bioinformatics analysis

JL Yang, CCN Wang, JH Cai, CY Chou, YC Lin… - Cancers, 2020 - mdpi.com
Bladder cancer is a common malignancy with mechanisms of pathogenesis and
progression. This study aimed to identify the prognostic hub genes, which are the central …

LncRNA weighted gene co-expression network analysis reveals novel biomarkers related to prostate cancer metastasis

M Liu, MY Chen, JM Huang, Q Liu, L Wang, R Liu… - BMC medical …, 2022 - Springer
Background Most prostate cancer patients die from metastasis and lack accurate efficacious
biomarkers to monitor the disease behavior, optimize treatment and assess prognosis …

Differentially expressed microRNAs in meningiomas grades I and II suggest shared biomarkers with malignant tumors

MR El-Gewely, M Andreassen, M Walquist, A Ursvik… - Cancers, 2016 - mdpi.com
Meningiomas represent the most common primary tumors of the central nervous system, but
few microRNA (miRNA) profiling studies have been reported so far. Deep sequencing of …

[HTML][HTML] Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

M Schmidt, A Mock, C Jungk, F Sahm, AT Ull, R Warta… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Meningiomas are frequent central nervous system tumors. Although most meningiomas are
benign (WHO grade I) and curable by surgery, WHO grade II and III tumors remain …

Identification of survival-associated hub genes in pancreatic adenocarcinoma based on WGCNA

L Huang, T Ye, J Wang, X Gu, R Ma, L Sheng… - Frontiers in …, 2022 - frontiersin.org
Pancreatic adenocarcinoma is one of the leading causes of cancer-related death worldwide.
Since little clinical symptoms were shown in the early period of pancreatic adenocarcinoma …

Investigation of miRNA and mRNA Co-expression Network in Ependymoma

F Liu, H Dong, Z Mei, T Huang - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Ependymoma (EPN) is a rare primary tumor of the central nervous system (CNS) that affects
both children and adults. Despite the definition and classification of distinct molecular …

RNA-seq transcriptome analysis of formalin fixed, paraffin-embedded canine meningioma

JK Grenier, PA Foureman, EA Sloma, AD Miller - PloS one, 2017 - journals.plos.org
Meningiomas are the most commonly reported primary intracranial tumor in dogs and
humans and between the two species there are similarities in histology and biologic …