Covering: 2008 to 2018 This review provides a comprehensive overview of newly
discovered natural products containing a tropolonoid motif covering 2008 up to 2018 and …

Phenylacetic acid (PAA) is a central intermediate metabolite involved in bacterial
degradation of aromatic components. The bacterial PAA pathway mainly contains 12 …

Streptomyces lividans is a suitable host for the heterologous expression of biosynthetic gene
clusters (BGCs) from actinomycetes to discover “cryptic” secondary metabolites. To improve …

Actinomycetes produce many of the drugs essential for human and animal health as well as
crop protection. Genome sequencing projects launched over the past two decades reveal …

Bacterial tropone natural products such as tropolone, tropodithietic acid, or the
roseobacticides play crucial roles in various terrestrial and marine symbiotic interactions as …

Tropone natural products are non‐benzene aromatic compounds of significant ecological
and pharmaceutical interest. Herein, we highlight current knowledge on bacterial tropones …

The newly discovered iron scavenger 7-hydroxytropolone (7-HT) is secreted by
Pseudomonas donghuensis HYS. In addition to possessing an iron-chelating ability, 7-HT …

Bacterial secondary metabolites represent an invaluable source of bioactive molecules for
the pharmaceutical and agrochemical industries. Although screening campaigns for the …

The genus Pseudomonas is a prolific source of specialized metabolites with significant
biological activities, including siderophores, antibiotics, and plant hormones. These …

Spiromaterpenes are a group of rare tropone-containing sesquiterpenes with
antineuroinflammatory activity. Herein, we elucidate their biosynthetic pathway in a deep …