Aims The diagnosis of periprosthetic joint infection (PJI) can be difficult. All current
diagnostic tests have problems with accuracy and interpretation of results. Many new tests …

The nature of implant-related infections is complex. Currently, there is no definitive test for
periprosthetic joint infection (PJI) and diagnosis remains challenging despite recent …

Aims The aim of this study was to determine the diagnostic accuracy of α defensin (AD)
lateral flow assay (LFA) and enzyme-linked immunosorbent assay (ELISA) tests for …

Background: The synovial fluid test for alpha defensin has been reported to have an
excellent performance in diagnosing periprosthetic joint infection (PJI). The purpose of this …

Abstract Purpose of Review The goal of this review is to provide an up to date understanding
of the utility and limitations of the current tests utilized in the diagnosis of periprosthetic joint …

Purpose Unexpected positive intraoperative cultures (UPIC) found in revision total knee
arthroplasty (TKA) are difficult to interpret. Management goes along with risks for both over …

Introduction: diagnosis of periprosthetic joint infection (PJI) is challenging, as no single test
has absolute accuracy. The purpose of this study was to assess the utility of different simple …

Background Alpha-defensin (AD) is a synovial biomarker included in the 2018 consensus
criteria for diagnosing periprosthetic joint infection (PJI). Its value in assessing eradication of …

Introduction Diagnosing infected joint replacements relies heavily on assessing the
neutrophil response to bacteria. Bacteria form biofilms on joint replacements. Biofilms are …

Background The utility of the synovial alpha-defensin test in diagnosing periprosthetic joint
infections (PJIs) remains controversial. This study aimed to examine the diagnostic utility of …