Schizophrenia is a debilitating psychiatric disorder that is treated with antipsychotics.
However, despite their efficacy, antipsychotics increase the risk of metabolic disorders in a …

Biomolecular condensates are membraneless organelles (MLOs) that form dynamic,
chemically distinct subcellular compartments organizing macromolecules such as proteins …

Fatty acids have long been considered essential to brain development; however, the
involvement of their synthesis in nervous system formation is unclear. We generate mice …

Abstract miR-124 is a miRNA predominantly expressed in the nervous system and accounts
for more than a quarter of the total miRNAs in the brain. It regulates neurogenesis, neuronal …

Treadmill exercise and mesenchymal stem cell transplantation are both practical and
effective methods for the treatment of cerebral ischemia. However, whether there is a …

Aducanumab, co-developed by Eisai (Japan) and Biogen (US), has received Food and Drug
Administration approval for treating Alzheimer's disease (AD). In addition, its successor …

GAP-43 is a vertebrate neuron-specific protein and that is strongly related to axon growth
and regeneration; thus, this protein has been utilized as a classical molecular marker of …

The establishment and maintenance of neuronal polarity are important for neural
development and function. Abnormal neuronal polarity establishment commonly leads to a …

In developing vertebrate neurons, a neurite is formed by more than a hundred microtubules.
While individual microtubules are dynamic, the microtubule array has been regarded as …

Introduction: Caveolin-1 and Caveolin-2 (CAV1 and CAV2) are proteins associated with
intercellular neurotrophic signalling. There is converging evidence that CAV1 and CAV2 …