Background Financial toxicity has traditionally been attributed to the rising costs of cancer
care. As ability to work impacts one's financial situation, limited employment and reduced …

As new pathogens emerge, new challenges must be faced. This is no different in infectious
disease research, where identifying the best tools available in laboratories to conduct an …

Positive-strand RNA viruses replicate in close association with rearranged intracellular
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …

Molecular virology tools are critical for basic studies of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and for developing new therapeutics. Experimental …

In light of the recent accumulated knowledge on SARS-CoV-2 and its mode of human cells
invasion, the binding of viral spike glycoprotein to human Angiotensin Converting Enzyme 2 …

Abstract Organ-on-a-chip (OOC, organ chip) technology can closely simulate the human
microenvironment, synthesize organ-like functional units on a fluidic chip substrate, and …

Drug repositioning represents an effective way to control the current COVID‐19 pandemic.
Previously, we identified 24 FDA‐approved drugs which exhibited substantial antiviral effect …

Two proteases produced by the SARS-CoV-2 virus, the main protease and papain-like
protease, are essential for viral replication and have become the focus of drug development …

The mucosa of the gastrointestinal tract, eyes, nose, lungs, cervix and vagina is lined by
epithelium interspersed with mucus-secreting goblet cells, all of which contribute to their …

Organ-on-a-chip is a microfluidic cell culture model that replicates key organ-specific
microarchitecture and pathophysiology in vitro. The current methods to fabricate these …