Hippocampal adult neurogenesis is thought to subserve pattern separation, the process by
which similar patterns of neuronal inputs are transformed into distinct neuronal …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping
neurodegenerative disorders whose pathogenesis remains largely unknown. Using TDP-43 …

Adult hippocampal neurogenesis (AHN) occurs in humans and every other mammalian
species examined. Evidence that AHN is stimulated by a variety of treatments and behaviors …

The hippocampus contains one of the few neurogenic niches within the adult brain—the
subgranular zone of the dentate gyrus. The functional significance of adult-born neurons in …

Sensorineural hearing loss (SNHL) has been demonstrated in many clinical reports as a risk
factor that promotes the development of cognitive impairment. However, the underlying …

The storage and persistence of memories depends on plasticity in the hippocampus. Adult
neurogenesis produces new neurons that mature through critical periods for plasticity and …

We propose that a major contribution of juvenile and adult hippocampal neurogenesis is to
allow behavioral experience to sculpt dentate gyrus connectivity such that sensory attributes …

Episodic memory is a complex process requiring input from several regions of the brain.
Emerging evidence suggests that coordinated activity between the dorsal hippocampus …

Early during their maturation, adult-born dentate granule cells (aDGCs) are particularly
excitable, but eventually develop the electrophysiologically quiet properties of mature cells …

The dentate gyrus (DG) receives substantial input from the homologous brain area of the
contralateral hemisphere. This input is by and large excitatory. Viral-tracing experiments …