The role of cell adhesion molecules in the progression of colorectal cancer and the development of liver metastasis

KA Paschos, D Canovas, NC Bird - Cellular signalling, 2009 - Elsevier
Cell adhesion molecules (CAMs) play a significant role in the metastatic potential of
colorectal cancer and thus mediate the prognosis of this common malignancy. The …

Pathobiology of colorectal cancer hepatic metastases with an emphasis on prognostic factors

MP LeGolvan, M Resnick - Journal of surgical oncology, 2010 - Wiley Online Library
Colorectal cancer is the second leading cause of cancer related death in the United States.
The majority of these deaths are due to metastasis, with the liver easily accounting as the …

[HTML][HTML] Acai (Euterpe oleracea Mart.) feeding attenuates dimethylhydrazine-induced rat colon carcinogenesis

MF Fragoso, GR Romualdo, DA Ribeiro… - Food and Chemical …, 2013 - Elsevier
This study investigated the protective effect of spray-dried açaí powder (AP) intake on colon
carcinogenesis induced by 1, 2-dimethylhydrazine (DMH) in male Wistar rats. After 4weeks …

Evaluation of the correlation of KAI1/CD82, CD44, MMP7 and β-catenin in the prediction of prognosis and metastasis in colorectal carcinoma

Q Wu, Y Yang, S Wu, W Li, N Zhang, X Dong, Y Ou - Diagnostic pathology, 2015 - Springer
Background To investigate the relationship of KAI1/CD82, CD44, matrix metalloproteinase 7
(MMP7) and β-catenin, and examine its association with clinicopathological features …

Leptin protein expression and promoter methylation in ovarian cancer: A strong prognostic value with theranostic promises

M Assidi, FM Yahya, MH Al-Zahrani, R Elkhatib… - International Journal of …, 2021 - mdpi.com
Ovarian cancer (OC) is the deadliest among all gynecological cancers. Epidemiological
studies showed that obesity might influence many cancers including OC. One of the key …

The prognostic value of the developmental gene FZD6 in young Saudi breast cancer patients: A biomarkers discovery and cancer inducers OncoScreen approach

M Assidi, A Buhmeida, MH Al-Zahrani… - Frontiers in Molecular …, 2022 - frontiersin.org
Wnt signalling receptors, Frizzleds (FZDs), play a pivotal role in many cellular events during
embryonic development and cancer. Female breast cancer (BC) is currently the worldwide …

Expression pattern, prognostic value and potential microRNA silencing of FZD8 in breast cancer

MH Al-Zahrani, M Assidi, PN Pushparaj… - Oncology …, 2023 - spandidos-publications.com
Breast cancer (BC) is one of the most widespread types of cancer affecting females, and
therefore, early diagnosis is critical. BC is a complex heterogeneous disease affected by …

Investigation of β-catenin and E-cadherin expression in Dukes B2 stage colorectal cancer with tissue microarray method. Is it a marker of metastatic potential in rectal …

L Tóth, C András, C Molnár, M Tanyi, Z Csiki… - Pathology & Oncology …, 2012 - Springer
Abstract β-catenin and E cadherin are both membrane-associated proteins which are
essential regulators and providers of cellular adhesion. In the metastatic cascade of …

Novel nitro-oxy derivatives of celecoxib for the regulation of colon cancer cell growth

F Bozzo, A Bassignana, L Lazzarato, D Boschi… - Chemico-biological …, 2009 - Elsevier
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) developed as a selective
inhibitor of cyclooxygenase-2 (COX-2). Despite the associated cardiovascular toxicity risk …

Prognostic value of E-Cadherin and its tumor suppressor role in Saudi women with advanced epithelial ovarian cancer

M Assidi, MA Jafri, M Abu-Elmagd… - Libyan Journal of …, 2021 - Taylor & Francis
The extracellular matrix (ECM) disruption and cytoskeleton reorganization are crucial events
in tumor proliferation and invasion. E-Cadherin (E-CAD) is a member of cell adhesion …