The eEF1 family of mammalian translation elongation factors is comprised of the two
variants of eEF1A (eEF1A1 and eEF1A2), and the eEF1B complex. The latter consists of …

The human translation machinery includes three types of supramolecular complexes
involved in elongation of the polypeptide chain: the ribosome, complex of elongation factors …

Abstract Background Esterase D (ESD) is a nonspecific esterase that detoxifies
formaldehyde. Many reports have stated that ESD activity is associated with a variety of …

Abstract Cyclosporin A (CsA) induces DNA double-strand breaks in LIG4 syndrome
fibroblasts, specifically upon transit through S-phase. The basis underlying this has not been …

Background: Ferroptosis was reported to possess the therapeutic potentials in various
human cancers. In the present study, we explored the expression, clinical significance and …

FKBP25 (FKBP3 gene) is a dual‐domain PPIase protein that consists of a C‐terminal
PPIase domain and an N‐terminal basic tilted helix bundle (BTHB). The PPIase domain of …

The FKBP39 from Drosophila melanogaster is a multifunctional regulatory immunophilin. It
contains two globular domains linked by a highly charged disordered region. The N-terminal …

Peptidyl prolyl isomerases (PPIase) are a class of enzymes that are required to catalyse the
conversion of proline residues from cis to trans conformation. There are several classes of …

25KD, FKBP25 knockdown; BTHB, Basic tilted helix bundle; Dox, doxycycline; FKBP25,
FK506 binding protein 25; Mir, MicroRNA, MTORC1, mechanistic target of rapamycin …

The RiboWest Conference brings together RNA researchers in Canada with the 2-fold goals
of fostering internationally competitive RNA research and of training the next generation of …