The extracellular matrix in ischemic and nonischemic heart failure
NG Frangogiannis - Circulation research, 2019 - Am Heart Assoc
The ECM (extracellular matrix) network plays a crucial role in cardiac homeostasis, not only
by providing structural support, but also by facilitating force transmission, and by transducing …
by providing structural support, but also by facilitating force transmission, and by transducing …
[HTML][HTML] The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms
JG Seidman, C Seidman - Cell, 2001 - cell.com
The Genetic Basis for Cardiomyopathy: Cell Skip to Main Content Advertisement Cell This
journal offers authors two options (open access or subscription) to publish research This …
journal offers authors two options (open access or subscription) to publish research This …
Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin
CN Toepfer, H Wakimoto, AC Garfinkel… - Science translational …, 2019 - science.org
The mechanisms by which truncating mutations in MYBPC3 (encoding cardiac myosin-
binding protein C; cMyBPC) or myosin missense mutations cause hypercontractility and …
binding protein C; cMyBPC) or myosin missense mutations cause hypercontractility and …
Striated muscle cytoarchitecture: an intricate web of form and function
KA Clark, AS McElhinny, MC Beckerle… - Annual review of cell …, 2002 - annualreviews.org
▪ Abstract Striated muscle is an intricate, efficient, and precise machine that contains
complex interconnected cytoskeletal networks critical for its contractile activity. The …
complex interconnected cytoskeletal networks critical for its contractile activity. The …
The molecular genetic basis for hypertrophic cardiomyopathy
AJ Marian, R Roberts - Journal of molecular and cellular cardiology, 2001 - Elsevier
Hypertrophic cardiomyopathy (HCM), a relatively common disease, is diagnosed clinically
by unexplained cardiac hypertrophy and pathologically by myocyte hypertrophy, disarray …
by unexplained cardiac hypertrophy and pathologically by myocyte hypertrophy, disarray …
Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice
SP Harris, CR Bartley, TA Hacker… - Circulation …, 2002 - Am Heart Assoc
Familial hypertrophic cardiomyopathy (FHC) is an inherited autosomal dominant disease
caused by mutations in sarcomeric proteins. Among these, mutations that affect myosin …
caused by mutations in sarcomeric proteins. Among these, mutations that affect myosin …
Phosphorylation and function of cardiac myosin binding protein-C in health and disease
D Barefield, S Sadayappan - Journal of molecular and cellular cardiology, 2010 - Elsevier
During the past 5 years there has been an increasing body of literature describing the roles
cardiac myosin binding protein C (cMyBP-C) phosphorylation play in regulating cardiac …
cardiac myosin binding protein C (cMyBP-C) phosphorylation play in regulating cardiac …
[HTML][HTML] Inherited cardiomyopathies: molecular genetics and clinical genetic testing in the postgenomic era
P Teekakirikul, MA Kelly, HL Rehm… - The Journal of Molecular …, 2013 - Elsevier
Inherited cardiomyopathies include hypertrophic cardiomyopathy, dilated cardiomyopathy,
arrhythmogenic right ventricular cardiomyopathy, left ventricular noncompaction, and …
arrhythmogenic right ventricular cardiomyopathy, left ventricular noncompaction, and …
Cardiac myosin binding protein C: its role in physiology and disease
E Flashman, C Redwood, J Moolman-Smook… - Circulation …, 2004 - Am Heart Assoc
Myosin binding protein-C (MyBP-C) is a thick filament–associated protein localized to the
crossbridge-containing C zones of striated muscle sarcomeres. The cardiac isoform is …
crossbridge-containing C zones of striated muscle sarcomeres. The cardiac isoform is …
Animal models to study cardiac arrhythmias
DJ Blackwell, J Schmeckpeper… - Circulation research, 2022 - Am Heart Assoc
Cardiac arrhythmias are a significant cause of morbidity and mortality worldwide, accounting
for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …
for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …