[HTML][HTML] Recent developments in lactose blend formulations for carrier-based dry powder inhalation

GA Hebbink, M Jaspers, HJW Peters… - Advanced Drug Delivery …, 2022 - Elsevier
Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …

Cocrystal engineering of pharmaceutical solids: Therapeutic potential and challenges

SN Wong, YCS Chen, B Xuan, CC Sun, SF Chow - CrystEngComm, 2021 - pubs.rsc.org
Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …

Lactose in tablets: Functionality, critical material attributes, applications, modifications and co-processed excipients

C Shi, H Zhao, Y Fang, L Shen, L Zhao - Drug Discovery Today, 2023 - Elsevier
Lactose is one of the most widespread excipients used in the pharmaceutical industry.
Because of its water solubility and acceptable flowability, lactose is generally added into …

Direct compression tablet containing 99% active ingredient—A tale of spherical crystallization

H Chen, A Aburub, CC Sun - Journal of pharmaceutical sciences, 2019 - Elsevier
Direct compression (DC) is the easiest and most cost-effective process for tablet
manufacturing, because it only involves blending and compression. However, active …

Spherical particles design of vanillin via crystallization method: Preparation, characterization and mechanism

X Xing, J Ouyang, S Guo, M Chen, Z Gao, F He… - Separation and …, 2023 - Elsevier
Vanillin is a natural flavor and is widely used in the fields of medicine, food and
optoelectronics. However, the stable form I of vanillin usually shows needle or fiber-like …

Application of lactose in the pharmaceutical industry

GA Hebbink, BHJ Dickhoff - Lactose, 2019 - Elsevier
This chapter describes the application of lactose as excipient in the pharmaceutical industry.
About 60%–70% of pharmaceutical dosage forms contain lactose, and in volume it is one of …

Microstructures and pharmaceutical properties of ferulic acid agglomerates prepared by different spherical crystallization methods

H Chen, C Wang, H Kang, B Zhi, CL Haynes… - International journal of …, 2020 - Elsevier
Spherical agglomerates of an active pharmaceutical ingredient, ferulic acid (FA), were
prepared using four different spherical crystallization methods, ie, quasi-emulsion solvent …

Development of piroxicam mini-tablets enabled by spherical cocrystallization

H Chen, C Wang, S Liu, CC Sun - International journal of pharmaceutics, 2020 - Elsevier
We examined the potential of the spherical cocrystallization (SCC) technology in
simultaneously enhancing tablet manufacturability and dissolution of poorly soluble drugs …

Physical and functional properties of cheese powders affected by sweet whey powder addition before or after spray drying

DF da Silva, L Ahrne, FH Larsen, AB Hougaard… - Powder Technology, 2018 - Elsevier
Cheese powder properties are affected by the use of different cheese raw materials, addition
of ingredients, spray drying and storage conditions. Sweet whey powder can be added after …

Effect of particle size and formulation on powder rheology

S Enferad, J Petit, C Gaiani, V Falk… - Particulate Science …, 2021 - Taylor & Francis
Links between flow properties and formulation of powders of 100 and 500 µm mean particle
sizes were investigated. To determine the influence of surface treatment, the flow properties …