Abstract β-Thalassemia is one of the most common monogenetic diseases worldwide, with a
particularly high prevalence in the Middle East region. As such, we have developed long …

The thalassaemias are a group of genetic disorders of haemoglobin which are endemic in
the tropics but are now found worldwide due to migration. Basic standard of care therapy …

Hemoglobinopathies are the most common single-gene disorders in the world. Their
prevalence is predicted to increase in the future, and low-income hemoglobinopathy …

Abstract β-Thalassemia is a hemoglobin genetic disorder characterized by the absence or
reduced β-globin chain synthesis, one of the constituents of the adult hemoglobin tetramer …

Background Familial hypercholesterolemia (FH) is a well-understood Mendelian disorder
that increases the risk of cardiovascular disease (CVD), a leading cause of mortality in …

Sickle cell disease (SCD) and thalassaemia are genetic disorders that are caused by errors
in the genes for haemoglobin and are some of the most common significant genetic …

Purpose Current practice recommendations support the widespread implementation of
reproductive genetic carrier screening (RGCS). These consensus-based recommendations …

Thalassemia is the most common monogenic inherited disease worldwide, affecting
individuals originating from many countries to various extents. As the disease requires long …

Background The MENA region is disproportionately affected by genetic disease. The aim of
this research is to scope the region for evidence of genetic services and public health …

Thalassemia and hemoglobinopathies are a major public health problem in Turkey.
Hemoglobinopathy prevention programs (HPPs) were started in 33 provinces situated in …