Biological effects of indole-3-propionic acid, a gut microbiota-derived metabolite, and its precursor tryptophan in mammals' health and disease

P Konopelski, I Mogilnicka - International journal of molecular sciences, 2022 - mdpi.com
Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

The Quest for Circulating Biomarkers in Neuroendocrine Neoplasms: a Clinical Perspective

L Mariën, O Islam, S Chhajlani, W Lybaert… - … Treatment Options in …, 2023 - Springer
Opinion statement Given the considerable heterogeneity in neuroendocrine neoplasms
(NENs), it appears unlikely that a sole biomarker exists capable of fully capturing all useful …

Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis

V Melone, A Salvati, D Palumbo, G Giurato… - Journal of translational …, 2022 - Springer
Abstract Background Neuroendocrine neoplasms (NENs) represent a heterogeneous class
of rare tumors with increasing incidence. They are characterized by the ability to secrete …

Neuroendocrine Tumors: Genomics and Molecular Biomarkers with a Focus on Metastatic Disease

ES Alexander, E Ziv - Cancers, 2023 - mdpi.com
Simple Summary Liver metastases secondary to neuroendocrine tumors (NETs) are
common at the time of diagnosis and are associated with worse quality of life and overall …

Biomarkers in small intestine NETs and carcinoid heart disease: A comprehensive review

M Kalligeros, L Diamantopoulos, C Toumpanakis - Biology, 2021 - mdpi.com
Simple Summary Neuroendocrine tumors (NET), a heterogeneous group of tumors arising
from neuroendocrine cells, often pose a diagnostic and therapeutic challenge for the …

Carcinoid Heart Disease Management: A Multi-Disciplinary Collaboration

S Das, SS Stockton, SA Hassan - The Oncologist, 2023 - academic.oup.com
Carcinoid heart disease (CaHD) is an important complication among patients with metastatic
neuroendocrine tumors and carcinoid syndrome (CS). CS patients (25%-65%) eventually …

Biomarkers to Inform Prognosis and Treatment for Unresectable or Metastatic GEP-NENs

JM Loree, D Chan, J Lim, H Stuart, N Fidelman… - JAMA …, 2024 - jamanetwork.com
Importance Evidence-based treatment decisions for advanced gastroenteropancreatic
neuroendocrine neoplasms (GEP-NENs) require individualized patient-centered decision …

[HTML][HTML] The role of the serotonergic system in atropine's anti-myopic effects

K Thomson, C Karouta, D Weber, N Hoffmann… - Biomedicine & …, 2023 - Elsevier
The muscarinic cholinergic antagonist atropine is the most widely used pharmacological
treatment for the visual disorder myopia (short-sightedness), the leading cause of low-vision …

Adverse effects of thimerosal on the early life stages of zebrafish

L Li, K Dong, LY Li, Q Li, Y Su, C Zong - Comparative Biochemistry and …, 2025 - Elsevier
Thimerosal (THI) is an organic mercury compound that is widely used in drugs, vaccines and
antibacterial products. Its extensive production and use have resulted in significant …

[HTML][HTML] Cardiac Surgery and Transcatheter Intervention for Valvular Heart Disease in Carcinoid Syndrome: Risk Factors, Outcomes, and Evolving Therapeutic …

M Piscione, V Cammalleri, G Antonelli… - Journal of …, 2024 - mdpi.com
Carcinoid heart disease (CHD) affects right-sided valves and causes significant mortality
and morbidity. Even though the pathophysiology of the disease is not entirely understood, it …