Hepatocellular carcinoma (HCC) is an aggressive disease with a poor clinical outcome. The
cancer stem cell (CSC) model states that tumour growth is powered by a subset of tumour …

Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

Hepatocellular carcinoma (HCC) contains a subset of cancer stem cells (CSC) that cause
tumor recurrence, metastasis, and chemical resistance. Histone deacetylase 11 (HDAC11) …

Histidine phosphorylation, the so-called hidden phosphoproteome, is a poorly characterized
post-translational modification of proteins,. Here we describe a role of histidine …

Emerging evidence in cancer metabolomics has identified reprogrammed metabolic
pathways to be a major hallmark of cancer, among which deregulated lipid metabolism is a …

Backgrounds The role of sphere-forming culture in enriching subpopulations with stem-cell
properties in hepatocellular carcinoma (HCC) is unclear. The present study investigates its …

Rationale CD13 is a new marker for liver cancer stem cells (CSCs) that contributes to
sorafenib resistance in hepatocellular carcinoma (HCC). However, the underlying …

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death, which develops
in the context of fibrosis and cirrhosis caused by chronic inflammation, in turn due to non …

Cancerous tumours contain a rare subset of cells with stem‐like properties that are termed
cancer stem cells (CSCs). CSCs are defined by their ability to divide both symmetrically and …

Cellular senescence is a complex physiological state whose main feature is proliferative
arrest. Cellular senescence can be considered the reverse of cell immortalization and …