Proteomics: technologies and their applications

B Aslam, M Basit, MA Nisar, M Khurshid… - Journal of …, 2016 - academic.oup.com
Proteomics involves the applications of technologies for the identification and quantification
of overall proteins present content of a cell, tissue or an organism. It supplements the other …

[HTML][HTML] MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice

M Aichler, A Walch - Laboratory investigation, 2015 - Elsevier
MALDI Imaging mass spectrometry has entered the field of tissue-based research by
providing unique advantages for analyzing tissue specimen in an unprecedented detail. A …

Advances in MALDI mass spectrometry imaging single cell and tissues

X Zhu, T Xu, C Peng, S Wu - Frontiers in Chemistry, 2022 - frontiersin.org
Compared with conventional optical microscopy techniques, mass spectrometry imaging
(MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique …

Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

Tissue penetration of antifungal agents

T Felton, PF Troke, WW Hope - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Understanding the tissue penetration of systemically administered antifungal agents is
critical for a proper appreciation of their antifungal efficacy in animals and humans. Both the …

Mass spectrometric imaging for biomedical tissue analysis

K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Imaging mass spectrometry

LA McDonnell, RMA Heeren - Mass spectrometry reviews, 2007 - Wiley Online Library
Imaging mass spectrometry combines the chemical specificity and parallel detection of mass
spectrometry with microscopic imaging capabilities. The ability to simultaneously obtain …

Mass spectrometry imaging with high resolution in mass and space

A Römpp, B Spengler - Histochemistry and cell biology, 2013 - Springer
Mass spectrometry (MS) imaging links molecular information and the spatial distribution of
analytes within a sample. In contrast to most histochemical techniques, mass spectrometry …

MALDI imaging mass spectrometry: molecular snapshots of biochemical systems

DS Cornett, ML Reyzer, P Chaurand, RM Caprioli - Nature methods, 2007 - nature.com
Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is
emerging as a powerful tool for investigating the distribution of molecules within biological …

Sublimation as a method of matrix application for mass spectrometric imaging

JA Hankin, RM Barkley, RC Murphy - Journal of the American …, 2007 - ACS Publications
Common organic matrix-assisted laser desorption/ionization (MALDI) matrices, 2, 5-
dihydroxybenzoic acid, 3, 5-dimethoxy-4-hydroxycinnamic acid, and α-cyano-4 …