α1-adrenergic receptors are G-Protein Coupled Receptors that are involved in
neurotransmission and regulate the sympathetic nervous system through binding and …

The locus coeruleus-norepinephrine (LC-NE) system is involved in many brain functions
and neurological disorders. In this review we discuss how LC-NE signaling affects the …

Background Before the deposition of amyloid-beta plaques and the onset of learning
memory deficits, patients with Alzheimer's disease (AD) experience olfactory dysfunction …

Olfactory receptors (ORs) and down-stream functional signaling molecules adenylyl cyclase
3 (AC3), olfactory G protein α subunit (Gαolf), OR transporters receptor transporter proteins 1 …

Evolutionarily, olfaction is one of the oldest senses and pivotal for an individual's health and
survival. The olfactory bulb (OB), as the first olfactory relay station in the brain, is known to …

Homotopic connectivity (HC) is the connectivity between mirror areas of the brain
hemispheres. It can exhibit a marked and functionally relevant spatial variability, and can be …

Highlights•Neuromodulators are widely represented throughout olfactory networks.•
Neuromodulators have diverse actions on cortical circuits.•Olfactory computations are …

Background Crustaceans express several classes of receptor genes in their antennules,
which house olfactory sensory neurons (OSNs) and non-olfactory chemosensory neurons …

The most important task of the olfactory system is to generate a precise representation of
odour information under different brain and behavioural states. As the first processing stage …

Decades of research confirm that noradrenergic locus coeruleus (LC) neurons are essential
for arousal, attention, motivation, and stress responses. While most studies on LC …