As FDA-approved small RNA drugs start to enter clinical medicine, ongoing studies for the
microRNA (miRNA) class of small RNAs expand its preclinical and clinical research …

There is an urgent unmet need for robust and reliable biomarkers for early diagnosis,
prognosis, and prediction of response to specific treatments of many aggressive and deadly …

The discovery of the link between microRNAs (miRNAs) and a myriad of human diseases,
particularly various cancer types, has generated significant interest in exploring their …

Innovative biomarkers are required to manage type 2 diabetic patients (T2DM). We focused
our study on miR-126-3p and miR-21-5p levels, as biomarkers of endothelial function and …

Aims ATP-binding cassette transporter A1 (ABCA1) mediates the efflux of cholesterol and
phospholipids to lipid-poor apolipoproteins, which then form nascent HDL, a key step in the …

Tissue ischemia, such as transient myocardial ischemia, leads to release of cellular RNA
including microRNA (miRNA) into the circulation and extracellular (ex-) space, but the …

Background. Recent studies have revealed the role of microRNAs (miRNAs) in a variety of
biological and pathological processes, including acute myocardial infarction (AMI). We …

Aortic dissection (AD) is the rupture of the aortic intima, causing the blood in the cavity to
enter the middle of the arterial wall. Without urgent and proper treatment, the mortality rate …

Background: Here, we determined miR-499 involvement in the protective effect of ischemic
postconditioning (IPC) against myocardial ischemia/reperfusion (I/R) injury and identified the …

Cisplatin (cis-Diaminedichloroplatinum) is one of the most effective chemotherapeutic
because of its anti-neoplastic properties against various types of tumor. However, it has a …