Gone Too Soon: priorities for action to prevent premature mortality associated with mental illness and mental distress
RC O'Connor, CM Worthman, M Abanga… - The Lancet …, 2023 - thelancet.com
Globally, too many people die prematurely from suicide and the physical comorbidities
associated with mental illness and mental distress. The purpose of this Review is to mobilise …
associated with mental illness and mental distress. The purpose of this Review is to mobilise …
[HTML][HTML] How to save a life: From neurobiological underpinnings to psychopharmacotherapies in the prevention of suicide
The impact of suicide on our societies, mental healthcare, and public health is beyond
questionable. Every year approximately 700 000 lives are lost due to suicide around the …
questionable. Every year approximately 700 000 lives are lost due to suicide around the …
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications
Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …
GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors
AR Docherty, N Mullins… - American journal of …, 2023 - Am Psychiatric Assoc
Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-
scale genome-wide association studies (GWASs) recently discovered and cross-validated …
scale genome-wide association studies (GWASs) recently discovered and cross-validated …
A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci
NA Kimbrel, AE Ashley-Koch, XJ Qin, JH Lindquist… - Molecular …, 2022 - nature.com
To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among
veterans, we conducted a genome-wide association study (GWAS) of suicide attempts within …
veterans, we conducted a genome-wide association study (GWAS) of suicide attempts within …
[HTML][HTML] Genome-wide association study meta-analysis of suicide death and suicidal behavior
Suicide is a worldwide health crisis. We aimed to identify genetic risk variants associated
with suicide death and suicidal behavior. Meta-analysis for suicide death was performed …
with suicide death and suicidal behavior. Meta-analysis for suicide death was performed …
[HTML][HTML] Shared genetic liability for alcohol consumption, alcohol problems, and suicide attempt: Evaluating the role of impulsivity
Heavy drinking and diagnosis with alcohol use disorder (AUD) are consistently associated
with risk for suicide attempt (SA). Though the shared genetic architecture among alcohol …
with risk for suicide attempt (SA). Though the shared genetic architecture among alcohol …
Identification of novel, replicable genetic risk loci for suicidal thoughts and behaviors among US military veterans
NA Kimbrel, AE Ashley-Koch, XJ Qin… - JAMA …, 2023 - jamanetwork.com
Importance Suicide is a leading cause of death; however, the molecular genetic basis of
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …
Suicidal behavior across a broad range of psychiatric disorders
YE Xu, DA Barron, K Sudol, S Zisook… - Molecular …, 2023 - nature.com
Suicide is a leading cause of death worldwide. In 2020, some 12.2 million Americans
seriously contemplated suicide, 3.2 million planned suicide attempts, and 1.2 million …
seriously contemplated suicide, 3.2 million planned suicide attempts, and 1.2 million …
Genome-wide investigation of maximum habitual alcohol intake in US veterans in relation to alcohol consumption traits and alcohol use disorder
Importance Alcohol genome-wide association studies (GWASs) have generally focused on
alcohol consumption and alcohol use disorder (AUD); few have examined habitual drinking …
alcohol consumption and alcohol use disorder (AUD); few have examined habitual drinking …