Purpose: To review the clinical picture, pathogenesis, and management of glucocorticoid-
induced osteoporosis. Data Identification: Studies published since 1970 were identified from …

The menstrual cycle is a reproductive vital sign and provides insight into hormonal
imbalance as well as pregnancy. The significance of estrogen, however, extends beyond …

Background Osteoporosis is a common complication of long-term glucocorticoid therapy for
which there is no well-proved preventive or restorative treatment. Methods We carried out …

Osteoporotic fractures are a major public health problem. It has been estimated that in the
USA the remaining lifetime fracture risk at the age of 50 years is 40% for white women and …

Glucocorticoids cause profound effects on bone cell replication, differentiation, and function.
Glucocorticoids increase bone resorption by stimulating osteoclastogenesis by increasing …

Osteoporosis is increasingly recognized as a source of significant disability, an awareness
that has prompted clinicians to actively pursue the diagnosis among high-risk patients …

Men and women (n= 518) receiving moderate-to-high doses of corticosteroids were enrolled
in two studies with similar protocols and randomly assigned to receive either placebo or …

Bone remodeling is regulated by systemic hormones and locally produced factors acting in
concert to maintain bone mass (1). In the adult skeleton, bone remodeling is a tightly …

To test the effect of 25 (OH) D3 (HyD) compared to vitamin D3 on serum 25‐hydroxyvitamin
D levels (25 (OH) D), lower extremity function, blood pressure, and markers of innate …

Oral glucocorticoids (GCs) are widely used and despite their adverse effects on bone
mineral density, the risk of sustaining osteoporotic fractures is not well addressed. The …