Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …

In vertebrates, exposure to diverse stressors during early life activates a stress response that
can initiate compensatory mechanisms or promote cellular damage with long-term fitness …

INTRODUCTION Early‐life stress (ES) increases the risk for Alzheimer's disease (AD). We
and others have shown that ES aggravates amyloid‐beta (Aβ) pathology and promotes …

Parent–infant bonds are critical early postnatal environment in mammals. Unstable parent–
infant bonds, such as maternal separation, paternal deprivation, and neonatal social …

Epidemiological evidence indicates that early life stress (ES) exposure increases the risk for
later-life diseases, such as Alzheimer's disease (AD). Accordingly, we and others have …

Microglia are relatively long-lived and self-sustainable macrophages of the central nervous
system (CNS). Microglia functions exceed the non-specific defense functions classically …