Infertility is a disease characterized by the failure to establish a clinical pregnancy after 12
months of regular and unprotected sexual intercourse. It is estimated to affect between 8 and …

Abstract Context European and North American guidelines recommend Y-chromosome
microdeletion (YCM) screening in azoospermic and oligozoospermic men with sperm …

A total of 3179 patients were screened for Y-chromosome microdeletions and 821 patients
for partial AZFc deletions. Thirty-nine Y-chromosomal microdeletions were found (2.4% of …

AZF microdeletion screening is routinely performed in the diagnostic work-up for male
infertility; however, some issues remain debated. In this study, we provide insights into the …

Objectives To determine the prevalence of Y chromosome microdeletions in infertile Korean
men with abnormal sperm counts and to assess the clinical features and frequency of …

The use of STR multiplexes with the incorporated gender marker Amelogenin is common
practice in forensic DNA analysis. However, when a known male sample shows a dropout of …

Background & objectives: Genetic factors contribute about 10 per cent of male infertility.
Among these, genes in azoospermia factor (AZF) region including AZFa, AZFb, AZFc and …

Background The role of X-linked genes and copy-number variations (CNVs) in male
infertility remains poorly explored. Our previous array-CGH analyses showed three recurrent …

Background Etiology of male infertility is intriguing and Y chromosome microdeletion within
azoospermia factor (AZF) sub‐regions is considered major cause. We conducted a …

A new DNA hybridization analytical method using a microfluidic channel and a molecular
beacon-based probe (MB-probe) is described. A stem-loop DNA oligonucleotide labeled …