Brain lesions in alcoholics are multifactorial in origin. Ethanol neurotoxicity, Wernicke's
encephalopathy, hepatocerebral degeneration, head trauma, central pontine myelinolysis …

The object of this review is to assemble much of the literature concerning Purkinje cell death
in cerebellar pathology and to relate this to what is now known about the complex …

This study examines the effect of chronic alcohol consumption on the human cerebellum
using operational criteria for case selection [Caine D. et al.(1997) J. Neurol. Neurosurg …

Severe, repetitive (“binge”) ethanol intoxication in adult rats (intragastric delivery 3 times
daily for 4 days in a modification of the Majchrowicz method) precipitates neuronal …

NMDA receptors are glutamate-gated ion channels, mediating excitatory neurotransmission
in the brain. These widely distributed receptors are known to play a role in neuronal …

The adverse effects of acute and chronic ethanol exposure on cerebellar functions have
been acknowledged for decades, in terms of impaired control of movement and balance. In …

There is evidence that chronic ethanol treatment (CET) disrupts the biological rhythms of
various brain functions and behaviors. Because the suprachiasmatic nucleus (SCN) is …

Objective: To examine the dose-response effect of alcohol consumption on the number of
cerebellar Purkinje cells. Design: A prospective necropsy study combined with detailed …

Acute consumption of ethanol results in reversible changes in learning and memory
whereas chronic ethanol consumption of six or more months produces permanent deficits …

The cerebellum is an important target of ethanol toxicity given that cerebellar ataxia is the
most consistent physical manifestation of acute ethanol consumption. Despite the …