Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Phosphatidylserine (PS) is an anionic phospholipid in the eukaryotic membrane and is
abundant in the brain. Accumulated studies have revealed that PS is involved in the multiple …

Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable
proportion of the human population and severely compromise quality of life. Therefore …

Schizophrenia (SZ) is a brain disorder that has been intensively studied for over a century;
yet, its etiology and multifactorial pathophysiology remain a puzzle. However, significant …

Sphingolipids (SFs) represent a large class of lipids playing diverse functions in a vast
number of physiological and pathological processes. Sphingomyelin (SM) is the most …

Emerging evidence points to the involvement of the brain extracellular matrix (ECM) in the
pathophysiology of schizophrenia (SZ). Abnormalities affecting several ECM components …

The past decade has witnessed an explosion of knowledge on the impact of glia for the
neurobiological foundation of schizophrenia. A plethora of studies have shown structural …

Lipids play an important role in neurodegeneration, neuroinflammation, and psychiatric
disorders and an imbalance in sphingolipid levels is associated with disease. Although early …

Indirect evidence for disturbed structural connectivity of subcortical fiber tracts in
schizophrenia has been obtained from functional neuroimaging and electrophysiologic …

Schizophrenia (SCZ) is the result of DNA alterations and environmental factors, which
together lead to differential protein expression and ultimately to the development of the …