Factor H is an essential regulatory protein that plays a critical role in the homeostasis of the
complement system in plasma and in the protection of bystander host cells and tissues from …

Outer retinal and renal glomerular functions rely on specialized vasculature maintained by
VEGF that is produced by neighboring epithelial cells, the retinal pigment epithelium (RPE) …

Purpose: Variants in the complement factor H (CFH) gene have been reported to be
associated with age-related macular degeneration (AMD). We conducted a case-control …

Age-related macular degeneration (AMD), the leading cause of severe vision loss in the
elderly, is a complex disease that results from genetic modifications that increase …

FHL-1/reconectin and factor H are two human complement regulators which are encoded by
a single gene. FHL-1/reconectin contains the first 7 of 20 SCR protein domains of factor H …

Aim To investigate the possible association between CFH gene polymorphisms− 543G> A
(rs1410996), A473A (rs2274700),− 257C> T (rs3753394), IVS15 (rs1329428) and AMD risk …

Purpose: The purpose of our study was to investigate the potential association between the
complement factor H (CFH)(rs3753394, rs800292, rs2284664, rs1329428, and rs1065489) …

purpose. This study was undertaken to investigate the association between the complement
factor H (CFH) gene and exudative age-related macular degeneration (AMD) in Korean …

Complement factor H (fH) is a member of a family of proteins involved in the regulation of
complement activation (RCA). These proteins share a common structural motif, the Short …

Factor H and the FHL-1/reconectin protein are two human plasma proteins that act as
important regulators of the alternative complement pathway. Each protein is encoded by a …