Neuregulins (NRGs) comprise a large family of growth factors that stimulate ERBB receptor
tyrosine kinases. NRGs and their receptors, ERBBs, have been identified as susceptibility …

Cognitive deficits are one of the core symptoms of schizophrenia that evolve during the
course of schizophrenia, after being originated even before the onset of illness. Existing …

Dynamical brain state transitions are critical for flexible working memory but the network
mechanisms are incompletely understood. Here, we show that working memory …

Defining the environmental context in which genes enhance disease susceptibility can
provide insight into the pathogenesis of complex disorders. We report that the intra-uterine …

While the hippocampal formation and the prefrontal cortex each have a well-established role
in cognitive and mnemonic processes, the extent and manner in which these structures …

The hippocampus and prefrontal cortex (PFC) have long been known to play a central role
in various behavioral and cognitive functions. More recently, electrophysiological and …

The panoply of cognitive, affective, motivational, and social functions that underpin everyday
human experience requires precisely choreographed patterns of interaction between …

We have used a translational convergent functional genomics (CFG) approach to identify
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …

There is substantial evidence for partial overlap of genetic influences on schizophrenia and
bipolar disorder, with family, twin, and adoption studies showing a genetic correlation …

Over 100 loci are now associated with schizophrenia risk as identified by single nucleotide
polymorphisms (SNPs) in genome-wide association studies. These findings mean that …