Gene function and cell surface protein association analysis based on single-cell multiomics data
Single-cell transcriptomics provides researchers with a powerful tool to resolve the
transcriptome heterogeneity of individual cells. However, this method falls short in revealing …
transcriptome heterogeneity of individual cells. However, this method falls short in revealing …
[HTML][HTML] Microarray data quality control improves the detection of differentially expressed genes
A Kauffmann, W Huber - Genomics, 2010 - Elsevier
Microarrays have become a routine tool for biomedical research. Data quality assessment is
an essential part of the analysis, but it is still not easy to perform objectively or in an …
an essential part of the analysis, but it is still not easy to perform objectively or in an …
[HTML][HTML] A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
We report the immediate effects of estrogen signaling on the transcriptome of breast cancer
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …
ArrayExpress update—trends in database growth and links to data analysis tools
G Rustici, N Kolesnikov, M Brandizi… - Nucleic acids …, 2012 - academic.oup.com
Abstract The ArrayExpress Archive of Functional Genomics Data (http://www. ebi. ac.
uk/arrayexpress) is one of three international functional genomics public data repositories …
uk/arrayexpress) is one of three international functional genomics public data repositories …
Navigating transcriptomic connectivity mapping workflows to link chemicals with bioactivities
Screening new compounds for potential bioactivities against cellular targets is vital for drug
discovery and chemical safety. Transcriptomics offers an efficient approach for assessing …
discovery and chemical safety. Transcriptomics offers an efficient approach for assessing …
ArrayExpress update—an archive of microarray and high-throughput sequencing-based functional genomics experiments
H Parkinson, U Sarkans, N Kolesnikov… - Nucleic acids …, 2010 - academic.oup.com
Abstract The ArrayExpress Archive (http://www. ebi. ac. uk/arrayexpress) is one of the three
international public repositories of functional genomics data supporting publications. It …
international public repositories of functional genomics data supporting publications. It …
Transfer of regulatory knowledge from human to mouse for functional genomics analysis
Transcriptome profiling followed by differential gene expression analysis often leads to lists
of genes that are hard to analyze and interpret. Functional genomics tools are powerful …
of genes that are hard to analyze and interpret. Functional genomics tools are powerful …
[HTML][HTML] curatedOvarianData: clinically annotated data for the ovarian cancer transcriptome
This article introduces a manually curated data collection for gene expression meta-analysis
of patients with ovarian cancer and software for reproducible preparation of similar …
of patients with ovarian cancer and software for reproducible preparation of similar …
[HTML][HTML] Unveiling sex-based differences in Parkinson's disease: a comprehensive meta-analysis of transcriptomic studies
A López-Cerdán, Z Andreu, MR Hidalgo… - Biology of sex …, 2022 - Springer
In recent decades, increasing longevity (among other factors) has fostered a rise in
Parkinson's disease incidence. Although not exhaustively studied in this devastating …
Parkinson's disease incidence. Although not exhaustively studied in this devastating …
[HTML][HTML] Proteome profiling in IL-1β and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis
T Mohr, V Haudek-Prinz, A Slany, J Grillari… - PloS one, 2017 - journals.plos.org
Endothelial cells represent major effectors in inflammation and angiogenesis, processes that
drive a multitude of pathological states such as atherosclerosis and cancer. Both …
drive a multitude of pathological states such as atherosclerosis and cancer. Both …