Gene function and cell surface protein association analysis based on single-cell multiomics data

H Hu, Z Feng, H Lin, J Cheng, J Lyu, Y Zhang… - Computers in Biology …, 2023 - Elsevier
Single-cell transcriptomics provides researchers with a powerful tool to resolve the
transcriptome heterogeneity of individual cells. However, this method falls short in revealing …

[HTML][HTML] Microarray data quality control improves the detection of differentially expressed genes

A Kauffmann, W Huber - Genomics, 2010 - Elsevier
Microarrays have become a routine tool for biomedical research. Data quality assessment is
an essential part of the analysis, but it is still not easy to perform objectively or in an …

[HTML][HTML] A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells

N Hah, CG Danko, L Core, JJ Waterfall, A Siepel, JT Lis… - Cell, 2011 - cell.com
We report the immediate effects of estrogen signaling on the transcriptome of breast cancer
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …

ArrayExpress update—trends in database growth and links to data analysis tools

G Rustici, N Kolesnikov, M Brandizi… - Nucleic acids …, 2012 - academic.oup.com
Abstract The ArrayExpress Archive of Functional Genomics Data (http://www. ebi. ac.
uk/arrayexpress) is one of three international functional genomics public data repositories …

Navigating transcriptomic connectivity mapping workflows to link chemicals with bioactivities

I Shah, J Bundy, B Chambers, LJ Everett… - Chemical research in …, 2022 - ACS Publications
Screening new compounds for potential bioactivities against cellular targets is vital for drug
discovery and chemical safety. Transcriptomics offers an efficient approach for assessing …

ArrayExpress update—an archive of microarray and high-throughput sequencing-based functional genomics experiments

H Parkinson, U Sarkans, N Kolesnikov… - Nucleic acids …, 2010 - academic.oup.com
Abstract The ArrayExpress Archive (http://www. ebi. ac. uk/arrayexpress) is one of the three
international public repositories of functional genomics data supporting publications. It …

Transfer of regulatory knowledge from human to mouse for functional genomics analysis

CH Holland, B Szalai, J Saez-Rodriguez - Biochimica et Biophysica Acta …, 2020 - Elsevier
Transcriptome profiling followed by differential gene expression analysis often leads to lists
of genes that are hard to analyze and interpret. Functional genomics tools are powerful …

[HTML][HTML] curatedOvarianData: clinically annotated data for the ovarian cancer transcriptome

BF Ganzfried, M Riester, B Haibe-Kains, T Risch… - Database, 2013 - academic.oup.com
This article introduces a manually curated data collection for gene expression meta-analysis
of patients with ovarian cancer and software for reproducible preparation of similar …

[HTML][HTML] Unveiling sex-based differences in Parkinson's disease: a comprehensive meta-analysis of transcriptomic studies

A López-Cerdán, Z Andreu, MR Hidalgo… - Biology of sex …, 2022 - Springer
In recent decades, increasing longevity (among other factors) has fostered a rise in
Parkinson's disease incidence. Although not exhaustively studied in this devastating …

[HTML][HTML] Proteome profiling in IL-1β and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis

T Mohr, V Haudek-Prinz, A Slany, J Grillari… - PloS one, 2017 - journals.plos.org
Endothelial cells represent major effectors in inflammation and angiogenesis, processes that
drive a multitude of pathological states such as atherosclerosis and cancer. Both …