Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition
KW Clancy, JA Melvin, DG McCafferty - Peptide Science, 2010 - Wiley Online Library
Gram‐positive bacteria pose a serious healthcare threat. The growing antibiotic resistance
epidemic creates a dire need for new antibiotic targets. The sortase family of enzymes is a …
epidemic creates a dire need for new antibiotic targets. The sortase family of enzymes is a …
[HTML][HTML] The divergent roles of sortase in the biology of Gram-positive bacteria
A Susmitha, H Bajaj, KM Nampoothiri - The Cell Surface, 2021 - Elsevier
The bacterial cell wall contains numerous surface-exposed proteins, which are covalently
anchored and assembled by a sortase family of transpeptidase enzymes. The sortase are …
anchored and assembled by a sortase family of transpeptidase enzymes. The sortase are …
Sequence characterisation and novel insights into bovine mastitis-associated Streptococcus uberis in dairy herds
B Vezina, H Al-Harbi, HR Ramay, M Soust… - Scientific Reports, 2021 - nature.com
Streptococcus uberis is one of the most frequent mastitis-causing pathogens isolated from
dairy cows. Further understanding of S. uberis genetics may help elucidate the disease …
dairy cows. Further understanding of S. uberis genetics may help elucidate the disease …
Dynamics of fecal microbial communities in children with diarrhea of unknown etiology and genomic analysis of associated Streptococcus lutetiensis
Background The sequences of the 16S rRNA genes extracted from fecal samples provide
insights into the dynamics of fecal microflora. This potentially gives valuable etiological …
insights into the dynamics of fecal microflora. This potentially gives valuable etiological …
Potential factors involved in the early pathogenesis of Streptococcus uberis mastitis: a review
AS Fessia, LM Odierno - Folia Microbiologica, 2021 - Springer
Bovine mastitis is an inflammation of the mammary gland, which could be the result of
allergy, physical trauma, or invasion by pathogens as Streptococcus uberis. This pathogen …
allergy, physical trauma, or invasion by pathogens as Streptococcus uberis. This pathogen …
Bacterial surface‐exposed lipoproteins and sortase‐mediated anchored cell surface proteins in plant infection
A de Sandozequi, C Martínez‐Anaya - MicrobiologyOpen, 2023 - Wiley Online Library
The bacterial cell envelope is involved in all stages of infection and the study of its
components and structures is important to understand how bacteria interact with the …
components and structures is important to understand how bacteria interact with the …
A comprehensive in silico analysis of sortase superfamily
A Malik, SB Kim - Journal of Microbiology, 2019 - Springer
Sortases are cysteine transpeptidases that assemble surface proteins and pili in their cell
envelope. Encoded by all Gram-positive bacteria, few Gram-negative bacteria and archaea …
envelope. Encoded by all Gram-positive bacteria, few Gram-negative bacteria and archaea …
[HTML][HTML] Sortase anchored proteins of Streptococcus uberis play major roles in the pathogenesis of bovine mastitis in dairy cattle
Streptococcus uberis, strain 0140J, contains a single copy sortase A (srtA), encoding a
transamidase capable of covalently anchoring specific proteins to peptidoglycan. Unlike the …
transamidase capable of covalently anchoring specific proteins to peptidoglycan. Unlike the …
Survival of Streptococcus uberis on bedding substrates
Streptococcus uberis (S. uberis) is a mastitis pathogen with an environmental reservoir.
Management factors related to housing design and bedding are associated with the risk of …
Management factors related to housing design and bedding are associated with the risk of …
[HTML][HTML] Assessment of the prevalence of Streptococcus uberis in dairy cow feces and implications for herd health
Streptococcus uberis is a major causative agent of bovine mastitis worldwide, negatively
affecting both milk production and animal welfare. Mammary infections result from …
affecting both milk production and animal welfare. Mammary infections result from …