Gram‐positive bacteria pose a serious healthcare threat. The growing antibiotic resistance
epidemic creates a dire need for new antibiotic targets. The sortase family of enzymes is a …

The bacterial cell wall contains numerous surface-exposed proteins, which are covalently
anchored and assembled by a sortase family of transpeptidase enzymes. The sortase are …

Streptococcus uberis is one of the most frequent mastitis-causing pathogens isolated from
dairy cows. Further understanding of S. uberis genetics may help elucidate the disease …

Background The sequences of the 16S rRNA genes extracted from fecal samples provide
insights into the dynamics of fecal microflora. This potentially gives valuable etiological …

Bovine mastitis is an inflammation of the mammary gland, which could be the result of
allergy, physical trauma, or invasion by pathogens as Streptococcus uberis. This pathogen …

The bacterial cell envelope is involved in all stages of infection and the study of its
components and structures is important to understand how bacteria interact with the …

Sortases are cysteine transpeptidases that assemble surface proteins and pili in their cell
envelope. Encoded by all Gram-positive bacteria, few Gram-negative bacteria and archaea …

Streptococcus uberis, strain 0140J, contains a single copy sortase A (srtA), encoding a
transamidase capable of covalently anchoring specific proteins to peptidoglycan. Unlike the …

Streptococcus uberis (S. uberis) is a mastitis pathogen with an environmental reservoir.
Management factors related to housing design and bedding are associated with the risk of …

Streptococcus uberis is a major causative agent of bovine mastitis worldwide, negatively
affecting both milk production and animal welfare. Mammary infections result from …