Using mouse models to investigate the pathophysiology, treatment, and prevention of post‐traumatic osteoarthritis
Post‐traumatic osteoarthritis (PTOA) is defined by its development after joint injury. Factors
contributing to the risk of PTOA occurring, the rate of progression, and degree of associated …
contributing to the risk of PTOA occurring, the rate of progression, and degree of associated …
[HTML][HTML] Osteoarthritis year in review 2014: mechanics–basic and clinical studies in osteoarthritis
The purpose of this review was to highlight recent research in mechanics and osteoarthritis
(OA) by summarizing results from selected studies spanning basic and clinical research …
(OA) by summarizing results from selected studies spanning basic and clinical research …
Current concepts on structure–function relationships in the menisci
The menisci are intricately organized structures that perform many tasks in the knee. We
review their structure and function and introduce new data about their tibial and femoral …
review their structure and function and introduce new data about their tibial and femoral …
Articular cartilage and sternal fibrocartilage respond differently to extended microgravity
J Fitzgerald, J Endicott, U Hansen, C Janowitz - npj Microgravity, 2019 - nature.com
The effects of spaceflight on cartilaginous structure are largely unknown. To address this
deficiency, articular cartilage (AC) and sternal cartilage (SC) from mice exposed to 30 days …
deficiency, articular cartilage (AC) and sternal cartilage (SC) from mice exposed to 30 days …
The effect of vigorous running and cycling on serum COMP, lubricin, and femoral cartilage thickness: a pilot study
HM Roberts, JP Moore, CL Griffith-McGeever… - European journal of …, 2016 - Springer
Purpose Our aim was to investigate lubricin, cartilage oligomeric matrix protein (COMP), and
femoral cartilage deformation in response to different biomechanical loading of the knee …
femoral cartilage deformation in response to different biomechanical loading of the knee …
In Vivo Dynamic Deformation of Articular Cartilage in Intact Joints Loaded by Controlled Muscular Contractions
When synovial joints are loaded, the articular cartilage and the cells residing in it deform.
Cartilage deformation has been related to structural tissue damage, and cell deformation …
Cartilage deformation has been related to structural tissue damage, and cell deformation …
Endogenous production of hyaluronan, PRG4, and cytokines is sensitive to cyclic loading in synoviocytes
Synovial fluid is composed of hyaluronan and proteoglycan-4 (PRG4 or lubricin), which work
synergistically to maintain joint lubrication. In diseases like osteoarthritis, hyaluronan and …
synergistically to maintain joint lubrication. In diseases like osteoarthritis, hyaluronan and …
Proteoglycan 4 is a diagnostic biomarker for COPD
Introduction The measurement of C-reactive protein (CRP) to confirm the stability of COPD
has been reported. However, CRP is a systemic inflammatory biomarker that is related to …
has been reported. However, CRP is a systemic inflammatory biomarker that is related to …
Primary cilia direct murine articular cartilage tidemark patterning through hedgehog signaling and ambulatory load
Articular cartilage (AC) is essential for body movement but is highly susceptible to
degenerative diseases and has poor self‐repair capacity. To improve current subpar …
degenerative diseases and has poor self‐repair capacity. To improve current subpar …
Mechanobiology-based physical therapy and rehabilitation after orthobiologic interventions: a narrative review
J McKay, M Nasb, K Hafsi - International Orthopaedics, 2022 - Springer
Purpose This review aims to summarize the evidence for the role of mechanotherapies and
rehabilitation in supporting the synergy between regeneration and repair after an …
rehabilitation in supporting the synergy between regeneration and repair after an …