Tumor microenvironment of hepatocellular carcinoma: challenges and opportunities for new treatment options
Z Sas, E Cendrowicz, I Weinhäuser… - International Journal of …, 2022 - mdpi.com
The prevalence of liver cancer is constantly rising, with increasing incidence and mortality in
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
PD-L1, TMB, and other potential predictors of response to immunotherapy for hepatocellular carcinoma: how can they assist drug clinical trials?
A Rizzo, AD Ricci - Expert opinion on investigational drugs, 2022 - Taylor & Francis
Introduction Hepatocellular carcinoma (HCC) represents the sixth most commonly
diagnosed malignancy worldwide, accounting for millions of deaths annually. Despite …
diagnosed malignancy worldwide, accounting for millions of deaths annually. Despite …
[PDF][PDF] Integrin subunit beta 8 contributes to lenvatinib resistance in HCC
W Hou, B Bridgeman, G Malnassy… - Hepatology …, 2022 - Wiley Online Library
Lenvatinib is a multikinase inhibitor approved as a first‐line therapy for advanced
hepatocellular carcinoma (HCC). However, the development of drug resistance is common …
hepatocellular carcinoma (HCC). However, the development of drug resistance is common …
Immunotherapies for hepatocellular carcinoma
JKH Liu, AF Irvine, RL Jones, A Samson - Cancer Medicine, 2022 - Wiley Online Library
Cases of hepatocellular carcinoma (HCC) are rapidly rising. This is particularly the case in
the Western world, as a result of increasing rates of chronic liver disease, secondary to …
the Western world, as a result of increasing rates of chronic liver disease, secondary to …
On efficacy of microwave ablation in the thermal treatment of an early-stage hepatocellular carcinoma
Simple Summary Hepatocellular carcinoma accounts for around 75% of all liver cancers,
and represents the fourth most common cause of cancer-related deaths worldwide …
and represents the fourth most common cause of cancer-related deaths worldwide …
Neoadjuvant therapy for hepatocellular carcinoma
Z Yin, D Chen, S Liang, X Li - Journal of hepatocellular carcinoma, 2022 - Taylor & Francis
Hepatocellular carcinoma (HCC) is characterized by low resection and high postoperative
recurrence rates, and conventional treatment strategies have failed to meet clinical needs …
recurrence rates, and conventional treatment strategies have failed to meet clinical needs …
A novel small-molecule antagonist enhances the sensitivity of osteosarcoma to cabozantinib in vitro and in vivo by targeting DNMT-1 correlated with disease severity …
JH Wang, Z Zeng, J Sun, Y Chen, X Gao - Pharmacological Research, 2021 - Elsevier
Advanced osteosarcoma (OSA) is highly aggressive and can lead to distant metastasis or
recurrence. Here, a novel small-molecule inhibitor/antagonist of DNA methyltransferase 1 …
recurrence. Here, a novel small-molecule inhibitor/antagonist of DNA methyltransferase 1 …
The association between metabolic risk factors, nonalcoholic fatty liver disease, and the incidence of liver cancer: a nationwide population-based cohort study
YG Chen, CW Yang, CH Chung, CL Ho, WL Chen… - Hepatology …, 2022 - Springer
Background and aims Liver cancer is a detrimental complication in patients with chronic viral
hepatitis and alcoholic or nonalcoholic fatty liver disease (NAFLD). However, metabolic risk …
hepatitis and alcoholic or nonalcoholic fatty liver disease (NAFLD). However, metabolic risk …
Long-term trends in incidence, mortality and burden of liver cancer due to specific etiologies in Hubei Province
H Liu, J Li, S Zhu, X Zhang, F Zhang, X Zhang… - Scientific Reports, 2024 - nature.com
Liver cancer, a chronic non-communicable disease, represents a serious public health
problem. Long-term trends in the burden of liver cancer disease are heterogeneous across …
problem. Long-term trends in the burden of liver cancer disease are heterogeneous across …
Effect of tertiary lymphoid structures on prognosis of patients with hepatocellular carcinoma and preliminary exploration of its formation mechanism
J Li, Y Nie, W Jia, W Wu, W Song, Y Li - Cancers, 2022 - mdpi.com
Simple Summary At present, research on tertiary lymphoid structures (TLSs) in
hepatocellular carcinoma (HCC) has been limited to the prognostic impact. Our manuscript …
hepatocellular carcinoma (HCC) has been limited to the prognostic impact. Our manuscript …