Most emerging and re-emerging infectious diseases stem from viruses that naturally
circulate in non-human vertebrates. When these viruses cross over into humans, they can …

Bats are known hosts for a wide range of coronaviruses (CoVs), including those that cause
severe acute respiratory syndrome (SARS-CoV-1) and Middle East respiratory syndrome …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution has resulted in
viral escape from clinically authorized monoclonal antibodies (mAbs), creating a need for …

Our comprehensive understanding of the multi-species ACE2 adaptiveness of
sarbecoviruses remains elusive, particularly for those with various receptor binding motif …

Microbial environmental DNA and RNA (collectively 'eNA') originate from a diverse and
abundant array of microbes present in environmental samples. These eNA signals, largely …

Introduction Bats are considered the natural reservoirs of several viruses including
coronaviruses (CoVs), two genera of which, alpha-and betacoronaviruses, infect humans …

DPP4 was considered a canonical receptor for merbecoviruses until the recent discovery of
African bat-borne MERS-related coronaviruses using ACE2. The extent and diversity with …

Diverse mammalian species display susceptibility to and infection with SARS-CoV-2.
Potential SARS-CoV-2 spillback into rodents is understudied despite their host role for …

Abstract Background PlMERS-CoV is a coronavirus known to cause severe disease in
humans, taxonomically classified under the subgenus Merbecovirus. Recent findings …

Increasing evidence suggests bats are the ancestral hosts of the majority of coronaviruses.
In general, coronaviruses primarily target the gastrointestinal system, while some strains …