Thyroid disease in pregnancy: new insights in diagnosis and clinical management

TIM Korevaar, M Medici, TJ Visser… - Nature Reviews …, 2017 - nature.com
Adequate thyroid hormone availability is important for an uncomplicated pregnancy and
optimal fetal growth and development. Overt thyroid disease is associated with a wide range …

Maternal thyroid dysfunction during pregnancy and the risk of adverse outcomes in the offspring: a systematic review and meta-analysis

GM Ge, MTY Leung, KKC Man… - The Journal of …, 2020 - academic.oup.com
Context Previous studies suggested a potential link of maternal thyroid dysfunction with
adverse neurocognitive outcomes and impaired development of internal organs in offspring …

[HTML][HTML] 2017 Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum

K AlexanderErik, N PearceElizabeth, A BrentGregory… - Thyroid, 2017 - liebertpub.com
Background: Thyroid disease in pregnancy is a common clinical problem. Since the
guidelines for the management of these disorders by the American Thyroid Association …

Maternal thyroid function during pregnancy and child brain morphology: a time window-specific analysis of a prospective cohort

TA Jansen, TIM Korevaar, TA Mulder… - The lancet Diabetes & …, 2019 - thelancet.com
Background Adequate thyroid hormone availability during pregnancy is necessary for
optimal fetal brain development. During the first 18–20 weeks of gestation, fetal thyroid …

Thyroid function in early pregnancy, child IQ, and autistic traits: a meta-analysis of individual participant data

D Levie, TIM Korevaar, SC Bath… - The Journal of …, 2018 - academic.oup.com
Context Low maternal free T4 (FT4) has been associated with poor child neurodevelopment
in some single-center studies. Evidence remains scarce for the potential adverse effects of …

Gut microbiota short-chain fatty acids and their impact on the host thyroid function and diseases

MJ Mendoza-León, AK Mangalam… - Frontiers in …, 2023 - frontiersin.org
Thyroid disorders are clinically characterized by alterations of L-3, 5, 3', 5'-tetraiodothyronine
(T4), L-3, 5, 3'-triiodothyronine (T3), and/or thyroid-stimulating hormone (TSH) levels in the …

Microbial endocrinology: host–bacteria communication within the gut microbiome

S Sandrini, M Aldriwesh, M Alruways… - Journal of …, 2015 - joe.bioscientifica.com
Isolated maternal hypothyroxinemia (IMH) during pregnancy is defined as a low maternal T
4 in the absence of TSH elevation. As IMH is common, with a prevalence of 1–2% in iodine …

Evaluating thyroid hormone disruption: investigations of long-term neurodevelopmental effects in rats after perinatal exposure to perfluorohexane sulfonate (PFHxS)

L Ramhøj, U Hass, ME Gilbert, C Wood, T Svingen… - Scientific Reports, 2020 - nature.com
Thyroid hormones are critical for mammalian brain development. Thus, chemicals that can
affect thyroid hormone signaling during pregnancy are of great concern. Perfluorohexane …

Management of endocrine disease: isolated maternal hypothyroxinemia during pregnancy: knowns and unknowns

C Dosiou, M Medici - European journal of endocrinology, 2017 - academic.oup.com
Isolated maternal hypothyroxinemia (IMH) during pregnancy is defined as a low maternal T4
in the absence of TSH elevation. As IMH is common, with a prevalence of 1–2% in iodine …

Clinical associations of maternal thyroid function with foetal brain development: epidemiological interpretation and overview of available evidence

TIM Korevaar, H Tiemeier, RP Peeters - Clinical Endocrinology, 2018 - Wiley Online Library
Thyroid hormone is an important regulator of early brain development, particularly during
early stages of gestation during which foetal thyroid hormone availability depends on the …